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N/A Completed N=87 Randomized Single-blind Basic Science

Effects of Narratives on Demand for Low and High Ventilated Cigarettes and Substitution for Alternative Products

Cigarette Smoking
Source: ClinicalTrials.gov NCT05487625 ↗
Enrolled (actual)
87
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcomePrimary: Nicotine/Tobacco Products Substitution Intercept — 16.4; 94.2; 47.8; 56.0 Mg of Nicotine purchased

Summary

This study will investigate the effects of narratives on demand for low and high ventilated cigarettes and substitution for alternative products in the Experimental Tobacco Marketplace.

Outcome Measures

OutcomeResultp-value
PRIMARY
Nicotine/Tobacco Products Substitution Intercept
16.4; 94.2; 47.8; 56.0; 12.1; 67.4
PRIMARY
Cigarette Demand Intensity q0
2509.951; 2446.043; 2002.901; 1226.371; 1389.097; 1201.065
PRIMARY
Nicotine/Tobacco Products Substitution Slope
13.24; -10.33; 1.96; 1.65; 11.50; -4.26
PRIMARY
Cigarette Demand Elasticity Alpha
0.0001184530; 0.0001866522; 0.0006728454; -0.004862780; 0.003933976; 0.002001107

Eligibility Criteria

Inclusion Criteria

  • Provide informed consent
  • Be at least 21 years of age or older
  • Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm)
  • Stable tobacco use patterns for at least three months
  • Be willing to sample the study cigarettes (high- and low-ventilated cigarettes)
  • Report smoking a high-ventilated cigarette (>= 20% ventilation)
  • Report smoking at least 10 cigarettes per day

Exclusion Criteria

  • Have plans to move out of the area
  • Have a serious or unstable physical or mental health condition
  • Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement
  • Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study

Note: Participants may be withdrawn from the study after providing consent if they submit an invalid breath sample (CO ≥ 8 ppm).

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05487625). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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