N/A
N=87
Effects of Narratives on Demand for Low and High Ventilated Cigarettes and Substitution for Alternative Products
Cigarette Smoking
Bottom Line
View on ClinicalTrials.gov: NCT05487625 ↗Enrolled (actual)
87
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Nicotine/Tobacco Products Substitution Intercept — 16.4; 94.2; 47.8; 56.0 Mg of Nicotine purchased
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- High-ventilated cigarette alone (Behavioral); Low-ventilated cigarette alone (Behavioral); High- and low-ventilated cigarette with high-ventilated cigarettes increasing in price (Behavioral); Low- and high-ventilated cigarette with high-ventilated cigarettes increasing in price (Behavioral); Usual, high- and low-ventilated cigarette with usual cigarettes increasing in price. (Behavioral)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- Virginia Polytechnic Institute and State University
- Primary completion
- Mar 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Nicotine/Tobacco Products Substitution Intercept |
16.4; 94.2; 47.8; 56.0; 12.1; 67.4 | — |
| PRIMARY Cigarette Demand Intensity q0 |
2509.951; 2446.043; 2002.901; 1226.371; 1389.097; 1201.065 | — |
| PRIMARY Nicotine/Tobacco Products Substitution Slope |
13.24; -10.33; 1.96; 1.65; 11.50; -4.26 | — |
| PRIMARY Cigarette Demand Elasticity Alpha |
0.0001184530; 0.0001866522; 0.0006728454; -0.004862780; 0.003933976; 0.002001107 | — |
Summary
This study will investigate the effects of narratives on demand for low and high ventilated cigarettes and substitution for alternative products in the Experimental Tobacco Marketplace.
Eligibility Criteria
Inclusion Criteria
- Provide informed consent
- Be at least 21 years of age or older
- Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm)
- Stable tobacco use patterns for at least three months
- Be willing to sample the study cigarettes (high- and low-ventilated cigarettes)
- Report smoking a high-ventilated cigarette (>= 20% ventilation)
- Report smoking at least 10 cigarettes per day
Exclusion Criteria
- Have plans to move out of the area
- Have a serious or unstable physical or mental health condition
- Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement
- Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study
Note: Participants may be withdrawn from the study after providing consent if they submit an invalid breath sample (CO ≥ 8 ppm).
Data sourced from ClinicalTrials.gov (NCT05487625). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.