N/A
Completed N=45
Interaural Frequency and Loudness Mismatch in SSD CI Users
Outcomes
Source: ClinicalTrials.gov NCT05494632 ↗
Enrolled (actual)
45
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcomePrimary: Speech Understanding in Noise, Measured With the R-Space Test Environment. The R-Space Test Environment Simulates Speech Understanding in a Noisy Restaurant. — -3.0; -1.9; -4.0; -2.9 signal-noise-ratio in decibels (dB) — p=<0.001
Summary
Interaural loudness and pitch mismatch in single-sided deaf cochlear implant (SSD-CI) recipients reduces binaural processing cues and contributes to performance outcomes, specifically speech understanding in noise and localization. The study aims to improve binaural cues through speech processor program modifications that reduce interaural mismatches.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Speech Understanding in Noise, Measured With the R-Space Test Environment. The R-Space Test Environment Simulates Speech Understanding in a Noisy Restaurant. |
-3.0; -1.9; -4.0; -2.9; -3.6; -2.9 | <0.001 sig |
Eligibility Criteria
Inclusion Criteria
- Participants for the proposed study will be adults with single-sided deafness. Participants will have at least 6 months experience with their cochlear implant or will be newly implanted with the cochlear implant.
Inclusion criteria for the experienced CI user group and the newly implant group are as follows:
- 18 years of age and older
- Postlingual onset of SSD
- Pure tone average (PTA) at 500, 1000, and 2000 Hz of less than or equal to 30 dB HL in the contralateral ear, known as the normal hearing ear
- Implanted with or chosen to be implanted with a Nucleus cochlear implant
- Full insertion of electrode array
Exclusion Criteria
- • Not meeting the inclusion criteria
Data sourced from ClinicalTrials.gov (NCT05494632). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.