N/A
N=314
Evaluation of PRYSHM for LGBTQIA2S+ Youth
Dating Violence · Alcohol Drinking
Bottom Line
View on ClinicalTrials.gov: NCT05521906 ↗Enrolled (actual)
314
Serious AEs
0.0%
Results posted
Apr 2025
Primary outcome: Primary: Intimate Partner Violence Perpetration at Week 21 — 5.79; 4.46 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Promoting Resilient Youth with Strong Hearts and Minds (PRYSHM) (Behavioral)
- Age
- Pediatric, Adult · 15+ yrs
- Sex
- All
- Sponsor
- University of Nebraska Lincoln
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intimate Partner Violence Perpetration at Week 21 |
5.79; 4.46 | — |
| PRIMARY Intimate Partner Violence Victimization at Week 21 |
5.57; 6.83 | — |
| PRIMARY Alcohol Use at Week 21 |
1.13; 1.86 | — |
| PRIMARY Sexual and Gender Minority Specific Intimate Partner Violence Perpetration at Week 21 |
0.04; 0.10 | — |
| PRIMARY Sexual and Gender Minority Specific Intimate Partner Violence Victimization at Week 21 |
0.35; 0.53 | — |
| PRIMARY Drinking Intentions at Week 21 |
1.50; 1.32 | — |
| PRIMARY Willingness to Drink at Week 21 |
1.20; 1.04 | — |
| SECONDARY Experience of Negative Consequences as a Result of Alcohol Use at Week 21 |
1.01; 1.26 | — |
| SECONDARY Depressive Symptoms at Week 21 |
9.07; 10.00 | — |
| SECONDARY Drug Use at Week 21 |
0.38; 0.44 | — |
| SECONDARY Sexual Risk-Taking as Measured by the Sexual Risk Survey at Week 21 |
2.13; 1.82 | — |
Summary
The overarching goal of the proposed project is to develop an innovative, online synchronous DV and AU prevention curriculum created specifically for SGMY (ages 15 to 18); conduct a pilot randomized controlled trial to assess its feasibility and acceptability of the intervention and study procedures; identify preliminary outcomes of the intervention; and ensure that the intervention is working equally well for SGMY of color.
Eligibility Criteria
Inclusion Criteria
- Self-identify as LGBTQIA2S+ (sexual and/or gender minority), and/or report being unsure of their sexual orientation, and/or report experiencing romantic/sexual attraction to someone of the same sex assigned at birth.
- Age between 15 and 18 years.
- Ability to read and speak in English.
- Current residence in the United States.
- Consistent access to an electronic device (e.g., smartphone, tablet, computer) with high speed Internet access and/or Wi-Fi.
- Ability to attend 9 weekly, one hour online intervention sessions.
- Recent or currently in a dating/romantic/sexual relationship (past three months).
- Not at high risk for suicide (as defined by not endorsing a critical item on a past-month suicide screening measure [SBQ-R], and/or not be deemed at elevated risk for suicide on the basis of a clinical interview,)
Exclusion Criteria
- Age under 15 or over 18 years.
- Identify as heterosexual and cisgender.
- Current enrollment as a full-time college student.
- Lack of English language proficiency (either written and/or spoken).
- Current residence outside of the U.S.
- No current or recent (in past three months) dating/romantic/sexual relationship.
- No consistent access to an electronic device (e.g., smartphone, tablet, computer) with high speed Internet or Wi-Fi.
- Inability to attend scheduled weekly one hour intervention sessions.
- Elevated risk of suicidality (reporting a past month suicide attempt or past month suicide threat with intent to die on the SBQ-R or determined to be at elevated current risk for suicidality based on a clinical interview).
Data sourced from ClinicalTrials.gov (NCT05521906). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.