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N/A N=16 Randomized Double-blind Prevention

Pilot Study on Training Emerging Adults Skills in Navigating College

Alcohol Abuse · Cognitive Deficit in Attention

Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Nov 2024
Primary outcome: Primary: Participant Retention — 85.71; 88.89 percentage of participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Koru Mindfulness (KM) Training (Behavioral); Navigating College (NC) Training (Behavioral)
Age
Adult · 18+ yrs
Sex
All
Sponsor
University of North Carolina, Chapel Hill
Primary completion
Dec 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Participant Retention
85.71; 88.89
PRIMARY
Compliance With Independent Training of Skills
10.43; 9.14 <0.05 sig
SECONDARY
Average CEQ Ratings - Credibility Subscale
15.29; 13.44
SECONDARY
Average CEQ Ratings - Expectancy Subscale
13.29; 14.00
SECONDARY
Mean Change in Emotional Distress Scores
8.8; 4.6; 3.2; 2.6; 2.4; 0.6
SECONDARY
Participant Satisfaction

Summary

Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to more frequent binge drinking, which is associated with more alcohol-related problems. Binge drinking is associated with deficits in behavioral flexibility, which may suggest impaired control networks that contribute to automatic behavior. Individuals with an alcohol or substance use disorder (A/SUD) exhibit attentional bias toward drug- or alcohol-related stimuli that have attained salience through consistent use. Reward history increases attention towards non-drug stimuli, even among individuals with no lifetime A/SUD. Preliminary data (from Dr. Boettiger's lab) from a nationally representative US adult sample using data collected via Prolific found that a questionnaire measure of mindfulness moderates the relationship between alcohol misuse and attention to reward. Given evidence that heavy alcohol drinking impairs behavioral flexibility, which in turn promotes escalating intake, insight into the relationship between mindfulness and behavioral flexibility could inspire new strategies to prevent alcohol and substance use disorders in people at elevated risk.

Eligibility Criteria

Inclusion Criteria

  • High school educated; college enrolled first-year student
  • Medically healthy
  • Ages 18-19
  • Native-English speaker (or fluent 4 lifetime binge drinking episodes (>4 drinks/2hours for females, >5 drinks/2 hours for males).

Exclusion Criteria

  • Psychiatric disease (such as depression or psychosis) using the MINI [25]
  • Systemic disease such as cancer, cardiovascular or inflammatory disease which could influence cognitive functioning
  • Motor or visual disturbance (e.g., colorblind)
  • Current use of psychoactive drugs (aside from moderate caffeine or alcohol), including prescription medications, or individuals with a known history of any substance use disorders (not including alcohol; including nicotine) or desire to seek treatment for excess substance (not including alcohol) use.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05560425). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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