N/A
N=16
Pilot Study on Training Emerging Adults Skills in Navigating College
Alcohol Abuse · Cognitive Deficit in Attention
Bottom Line
View on ClinicalTrials.gov: NCT05560425 ↗Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Nov 2024
Primary outcome: Primary: Participant Retention — 85.71; 88.89 percentage of participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Koru Mindfulness (KM) Training (Behavioral); Navigating College (NC) Training (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of North Carolina, Chapel Hill
- Primary completion
- Dec 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Participant Retention |
85.71; 88.89 | — |
| PRIMARY Compliance With Independent Training of Skills |
10.43; 9.14 | <0.05 sig |
| SECONDARY Average CEQ Ratings - Credibility Subscale |
15.29; 13.44 | — |
| SECONDARY Average CEQ Ratings - Expectancy Subscale |
13.29; 14.00 | — |
| SECONDARY Mean Change in Emotional Distress Scores |
8.8; 4.6; 3.2; 2.6; 2.4; 0.6 | — |
| SECONDARY Participant Satisfaction |
— | — |
Summary
Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to more frequent binge drinking, which is associated with more alcohol-related problems. Binge drinking is associated with deficits in behavioral flexibility, which may suggest impaired control networks that contribute to automatic behavior. Individuals with an alcohol or substance use disorder (A/SUD) exhibit attentional bias toward drug- or alcohol-related stimuli that have attained salience through consistent use. Reward history increases attention towards non-drug stimuli, even among individuals with no lifetime A/SUD. Preliminary data (from Dr. Boettiger's lab) from a nationally representative US adult sample using data collected via Prolific found that a questionnaire measure of mindfulness moderates the relationship between alcohol misuse and attention to reward. Given evidence that heavy alcohol drinking impairs behavioral flexibility, which in turn promotes escalating intake, insight into the relationship between mindfulness and behavioral flexibility could inspire new strategies to prevent alcohol and substance use disorders in people at elevated risk.
Eligibility Criteria
Inclusion Criteria
- High school educated; college enrolled first-year student
- Medically healthy
- Ages 18-19
- Native-English speaker (or fluent 4 lifetime binge drinking episodes (>4 drinks/2hours for females, >5 drinks/2 hours for males).
Exclusion Criteria
- Psychiatric disease (such as depression or psychosis) using the MINI [25]
- Systemic disease such as cancer, cardiovascular or inflammatory disease which could influence cognitive functioning
- Motor or visual disturbance (e.g., colorblind)
- Current use of psychoactive drugs (aside from moderate caffeine or alcohol), including prescription medications, or individuals with a known history of any substance use disorders (not including alcohol; including nicotine) or desire to seek treatment for excess substance (not including alcohol) use.
Data sourced from ClinicalTrials.gov (NCT05560425). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.