N/A
Completed N=24
The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine
Source: ClinicalTrials.gov NCT05568004 ↗Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcomePrimary: Change in the Number of Days With Migraine (in Migraine Frequency) — 9.9; 12.4; 11.8; 6.3 days/month — p=0.001
Summary
The purpose of this study is to evaluate and compare the effect of different exercise types and combinations on migraine attacks in patients with migraine.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in the Number of Days With Migraine (in Migraine Frequency) |
9.9; 12.4; 11.8; 6.3; 8; 10.6 | 0.001 sig |
| SECONDARY Average Intensity of Headache |
7; 7.5; 7.4; 6.3; 6.8; 7 | 0.074 |
| SECONDARY Anxiety |
10.3; 7.8; 6.3; 8.5; 6; 6.3 | 0.018 sig |
| SECONDARY Depression |
7; 6.8; 5.4; 5.6; 5.8; 4.9 | 0.135 |
| SECONDARY Migraine Specific Quality of Life |
49; 46.8; 42.8; 32.1; 30.6; 39.5 | 0.001 sig |
| SECONDARY Aerobic Capacity Measurement V02 Max |
30.1; 29.5; 28; 33.4; 32.5; 28.1 | <0.001 sig |
| SECONDARY Change in Physical Activity Level |
565.1; 585.1; 415.1; 1338.4; 1542.4; 660.8 | 0.001 sig |
Eligibility Criteria
Inclusion Criteria
- A diagnosis of migraine confirmed by a specialist neurologist according to International Classification of Headache Disorders, 3rd version(ICHD-3)
- Diagnosed as chronic migraine at the time of initial diagnosis (may have turned into episodic migraine under preventive treatment)
- At least 5 migraine attack/month in baseline diary
- No obstacle to exercise in the evaluation made with physical examination and ECG
- Diagnosed with migraine for at least 12 months
- Between the ages of 18-50
Exclusion Criteria
- Exercising regularly in the last 6 months
- Presence of concomitant internal and neurological diseases
- Anti-psychotic drug use
- Drug, alcohol addiction
- Pregnancy, breastfeeding
- Patients who cannot reach the targeted exercise level
Data sourced from ClinicalTrials.gov (NCT05568004). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.