N/A
Completed N=11
Cerebrovascular Dysregulation in Chronic Kidney Disease
Chronic Kidney Diseases
Source: ClinicalTrials.gov NCT05571605 ↗
Enrolled (actual)
11
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcomePrimary: Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Phase (Radians) — 1.38; 1.12; 1.40; 1.60 Radians — p=0.05
Summary
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Phase (Radians) |
1.38; 1.12; 1.40; 1.60 | 0.05 |
| PRIMARY Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Gain (cm/s/mmHg) |
0.65; 0.67; 0.77; 0.63 | — |
Eligibility Criteria
Inclusion Criteria
- Individuals with chronic kidney disease stages III-IV.
Exclusion Criteria
- Heart failure
- Chronic obstructive pulmonary disease
- Uncontrolled hypertension or hypotension
- Pregnancy or plans to become pregnant
- Inability to exercise on a stationary bicycle
- Current participation in exercise more than 20 minutes twice per week
Data sourced from ClinicalTrials.gov (NCT05571605). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.