N/A
N=11
Cerebrovascular Dysregulation in Chronic Kidney Disease
Chronic Kidney Diseases
Bottom Line
View on ClinicalTrials.gov: NCT05571605 ↗Enrolled (actual)
11
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Phase (Radians) — 1.38; 1.12; 1.40; 1.60 Radians — p=0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Exercise (Behavioral); Stretching (Behavioral)
- Age
- Adult, Older Adult · 30+ yrs
- Sex
- All
- Sponsor
- University of North Texas, Denton, TX
- Primary completion
- Feb 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Phase (Radians) |
1.38; 1.12; 1.40; 1.60 | 0.05 |
| PRIMARY Mean Arterial Pressure-Middle Cerebral Artery Blood Velocity Very Low Frequency Gain (cm/s/mmHg) |
0.65; 0.67; 0.77; 0.63 | — |
Summary
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
Eligibility Criteria
Inclusion Criteria
- Individuals with chronic kidney disease stages III-IV.
Exclusion Criteria
- Heart failure
- Chronic obstructive pulmonary disease
- Uncontrolled hypertension or hypotension
- Pregnancy or plans to become pregnant
- Inability to exercise on a stationary bicycle
- Current participation in exercise more than 20 minutes twice per week
Data sourced from ClinicalTrials.gov (NCT05571605). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.