Mode
Text Size
Log in / Sign up
N/A N=30

Can a Dedicated Chronic Limb-threatening Ischaemia (CLTI) Clinic Improve Patient Self-reported Quality of Life

Chronic Limb Threatening Ischemia

Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: EuroQoL-5D Visual Acuity Scale (VAS) Score — 47.55; 69.15; 65.35 score on a scale — p=0.005

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
CLTI Clinic (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The Leeds Teaching Hospitals NHS Trust
Primary completion
Aug 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
EuroQoL-5D Visual Acuity Scale (VAS) Score
47.55; 69.15; 65.35 0.005 sig
SECONDARY
EuroQoL-5D Movement
0; 2; 2; 4; 7; 6 0.388
SECONDARY
EuroQoL-5D Self Care
8; 9; 4; 4; 4; 4 0.974
SECONDARY
EuroQoL 5-D Usual Activities
2; 6; 4; 5; 6; 7 0.118
SECONDARY
EuroQoL 5-D Pain
1; 9; 2; 4; 6; 3 0.018 sig
SECONDARY
EuroQoL 5-D Anxiety and/or Depression
5; 10; 6; 1; 6; 9 0.190

Summary

CLTI is the most severe form of peripheral arterial disease. Patients with the condition require investigation and management (typically in the form of revascularisation surgery) to salvage the limb. Traditionally, patients with the condition are admitted into hospital for their management, but with the advent of regional vascular networks, this is becoming increasingly difficult. Recently, the Vascular Society of Great Britain and Ireland have advocated for the use of dedicated CLTI clinics to overcome this problem. Whilst there is burgeoning evidence for their clinical benefit, there is a lack of patient reported outcomes to measure their impact on patient selr-reported quality of life. We would like to determine if this service benefits its users as much as the clinical outcomes suggest it does.

Eligibility Criteria

Inclusion Criteria

  • All patients seen and assessed in the CLTI clinic

Exclusion Criteria

  • Patients without a confirmed diagnosis of CLTI
  • Patients with chronic venous insufficiency
  • Patients with diabetic foot infection
  • Patients with significant cognitive impairment such that they are unable to answer the questions
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05613907). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search