N/A
N=170
Intubating Conditions of Neuromuscular Blockade
Endotracheal Intubation
Bottom Line
View on ClinicalTrials.gov: NCT05620108 ↗Enrolled (actual)
170
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Number of Subjects With Optimal Intubating Conditions — 61; 47 Participants — p=0.036
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Endotracheal Intubation at TOFC=1 (Procedure); Endotracheal Intubation 2 minutes after rocuronium administration (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Nov 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Subjects With Optimal Intubating Conditions |
61; 47 | 0.036 sig |
Summary
The purpose of this research is to learn about the difference in the endotracheal intubation condition (ease of using a device to view vocal cords, position of vocal cords, and patient's reaction to endotracheal tube insertion) and determining the appropriate time to perform the intubation.
Eligibility Criteria
Inclusion Criteria
- Patients willing to participate and provide an informed consent.
- Patients undergoing elective surgical procedures that require use of NMBA agents (rocuronium) administered intraoperatively.
Exclusion Criteria
- Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
- Patients with systemic neuromuscular diseases such as myasthenia gravis.
- Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents; i.e., severe renal impairment or end-stage liver disease.
- Patients having surgery that would involve prepping the arm into the sterile field.
- Patients receiving a rapid sequence induction.
Data sourced from ClinicalTrials.gov (NCT05620108). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.