Phase 2
Completed N=5
Erector Spinae Plane Block for Uncomplicated Renal Colic
Renal Colic · Kidney Stone
Source: ClinicalTrials.gov NCT05625802 ↗
Enrolled (actual)
5
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcomePrimary: Participants Who Received a Second Parenteral Pain Medication in the Emergency Department (ED) — 0 Participants
Summary
This research study is to determine how well the Erector Spinae Plane Block (ESPB) works for kidney stone pain and any possible side effects.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Participants Who Received a Second Parenteral Pain Medication in the Emergency Department (ED) |
— | — |
| SECONDARY Change in Pain |
3.2; 1.8; 1.8 | — |
| SECONDARY Rate of Admission to Hospital for Kidney Stones |
2; 1 | — |
| SECONDARY Rate of 24-hour and 72-hour Return to the Emergency Department (ED) |
0; 0 | — |
| SECONDARY Emergency Department Length of Stay |
418 | — |
| SECONDARY Safety Outcomes and Complications |
0; 0; 0; 0; 0; 0 | — |
Eligibility Criteria
Inclusion Criteria
- Imaging confirmation of urolithiasis on the index encounter or prior encounter within 7 days
- Patient received one dose of parenteral pain medication in the emergency department (ED)
Exclusion Criteria
- Pregnancy or breastfeeding
- Prisoner or incarcerated individual
- Therapeutic anticoagulation or coagulopathy.
- Active treatment for urinary tract infection (either acute infection or chronic therapy)
- Prior spinal surgery in the thoracic region
- Allergy to local anesthetic or prior local anesthetic
- Soft tissue infection overlying the injection site
- Positive for coronavirus
- Inability to communicate verbally or read/write in English
- Currently taking strong CYP1A2 inhibitor (fluvoxamine, amiodarone, fluoroquinolones, etc.)
- Glucose-6-phosphate dehydrogenase deficiency (G6PD)
Data sourced from ClinicalTrials.gov (NCT05625802). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.