Endorail in Long Lasting Colonoscopy

Inclusion Criteria

• Patients of both sexes aged between 22 - 75 years (inclusive);
• Outpatients undergoing long-lasting diagnostic and surveillance colonoscopy; long-lasting colonoscopy is defined as follows: colonoscopy completion (caecal intubation) not achieved after 10 minutes from endoscope insertion through the anal canal;
• Patients have given a written informed consent for participation in the study at the time of enrolment or before;
• Patients able to understand the full nature and the purpose of the investigation, including possible risks and side effects, able to cooperate with the Investigator and to comply with the requirements of the entire investigation based on Investigator's judgement.

Exclusion Criteria

• Body mass index (BMI) > 30 kg/m2;
• Outpatients undergoing colonoscopy for colorectal cancer screening or therapeutic indication;
• Patients in class >2 physical status of the classification system of American Society of Anaesthesiologists;
• Any contraindications to colonoscopy;
• Any contraindications to sedation;
• Known allergy or hypersensitivity to any of the elements of the Endorail Set (e.g.: iron);
• Patients with permanently or semi-permanently implanted medical devices, (e.g. orthopedic implants, trauma fixation devices, cardiac pacemakers, implantable cardioverter defibrillator, drug pumps, neurostimulators, vascular stents, cochlear implants, aneurysm clip);
• Presence of dense diverticulosis
• Presence of diverticulitis
• Presence of ferromagnetic foreign body;
• Presence of large abdominal hernias;
• Presence of severe thrombocytopenia;
• Presence of severe granulocytopenia;
• Presence of severe coagulopathy;
• Presence of peritonitis;
• Presence of colonic wall ischemia or necrosis or injured mucosa;
• Presence of peritoneal carcinomatosis;
• Boston Bowel Preparation Scale <2 in at least one of the colonic segments;
• Presence of obstructing masses and strictures of the colon;
• History of total or subtotal colectomy.
• Presence of angulated and fixed colon curves;
• Pregnant or breast-feeding women;
• Patient unable to provide the signed informed consent, uncooperative patient or patient unlikely to comply with the protocol or unable to understand the nature, scope and possible consequences of the study;
• Presence of any other reason that, in the opinion of the investigator, prevents the subject from participating in the study or compromises the subject safety
• Concomitant participation in other clinical investigations or participation in the evaluation of any investigational product/device in the 30 days before this study or previous participation in the same investigation;
• Urgent colonoscopy.