N/A
Completed N=84
Effect of Interceptive Strategies on the Clinical Outcome of Maxillary Impacted Canines
Tooth, Impacted
Source: ClinicalTrials.gov NCT05629312 ↗
Enrolled (actual)
84
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcomePrimary: Number of Definitive Upper Canines That Erupt Spontaneously up to 18 Months of Follow up — 3; 2; 1; 4 number of canines
Summary
This study aims to investigate the effect of 3 randomly applied interceptive measures (slow maxillary expansion, extraction of deciduous canines and no intervention) on maxillary canine impaction in patients with early mixed dentition and lack of space in the dental arch. Additionally, these groups are compared with a control group with adequate space. Patients with at least one impacted maxillary canine, presence of deciduous canines and absence of crossbite were included. The canine position is assessed by measuring five variables (sector of the canine cusp, canine to midline angle, canine to first premolar angle, canine cusp to midline distance, and canine cusp to maxillary plane distance) on 2 panoramic radiographs at 0 (T1) and 18 months (T2).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Definitive Upper Canines That Erupt Spontaneously up to 18 Months of Follow up |
3; 2; 1; 4 | — |
| PRIMARY Number of Definitive Upper Canines That Erupt Spontaneously After 18 Months of Follow up |
4; 4; 6; 15 | — |
| SECONDARY Sector Where the Canine is Located |
-0.22; -0.15; 0.11; -0.10 | — |
| SECONDARY Angulation of the Canine Towards the Dental Midline |
-11.85; -8.16; -7.68; -11.29 | — |
| SECONDARY Angulation of the Canine Towards the First Premolar |
-2.27; -3.13; 0.08; -2.57 | — |
| SECONDARY Distance Between the Canine Cusp and the Midline |
0.83; 0.57; -0.51; 1.77 | — |
| SECONDARY Distance Between the Canine Cusp and the Occlusal Plane |
-6.31; -4.79; -7.10; -9.14 | — |
| SECONDARY Need for Further Minor and/or Major Orthodontic Intervention |
8; 2; 0; 5; 4; 9 | — |
Eligibility Criteria
Inclusion Criteria
- All patients presenting at the intake consultation of the Department of Orthodontics of University Hospitals Leuven, Belgium from September 2016, with at least one maxillary permanent canine impaction are invited to participate. Canine impaction is diagnosed based on a panoramic radiograph, taken for standard evaluation of dental development and associated pathology. A maxillary canine is considered to be impacted when the canine to midline angle was ≥15° (Alqerban et al. 2014; Warford et al. 2003). Only impacted maxillary canines with incomplete root formation and with persisting deciduous canines are included.
Exclusion Criteria
- presence of uni- or bilateral posterior dental crossbite,
- upper permanent canines showing root malformation, ankylosis or fully erupted,
- evidence of root resorption of adjacent teeth, previous orthodontic treatment,
- craniofacial syndromes,
- systemic disease that would impede orthodontic treatment/surgery and recent exposure to radiotherapy.
- large eruption follicles seen on the permanent canines
Data sourced from ClinicalTrials.gov (NCT05629312). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.