N/A N=10 Treatment

Temperature Profiles During Laser Activation in Ureteroscopic Lithotripsy

Ureteral Stone

Bottom Line

View on ClinicalTrials.gov: NCT05677425 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2025

Primary outcome: Primary: Temperature Profiles — 32.5; 35.3; 37.9; 40.0 Degrees Celcius

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Temperature measurement (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Haukeland University Hospital
Primary completion: Jun 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Temperature Profiles	32.5; 35.3; 37.9; 40.0	—

Summary

The primary aim of this study is to investigate the temperature profiles in the renal pelvis during ureteroscopic Thulium Fiber Laser activation using different settings. To this end, comparison of peak temperatures during laser activation for different settings is the main aim. Secondary aim is trying to define the duration of safe laser activation until the threshold for heat induced cell injury (43oC) is reach. Patients ≥ 18 years with a ureteral stone (with or without a concomitant renal stone) and an indwelling nephrostomy tube scheduled for ureteroscopic lithotripsy at the day surgery unit at Haukeland University Hospital, are eligible to enrolment in the study. Temperature measurements during ureteroscopic laser stone disintegration will be performed. Follow-up is standardised with clinical consultation and low dose CT 3 months post endoscopically.

Eligibility Criteria

Inclusion Criteria

Patients ≥ 18 years with a ureteral stone (with or without a concomitant renal stone) and an indwelling nephrostomy tube scheduled for URS lithotripsy at the Day Surgery unit at Haukeland University Hospital

Exclusion Criteria

Urinary diversion
Active infection
Untreated cancer in the upper urinary tract

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05677425). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.