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N/A N=11 Treatment

A Prospective Evaluation of Infraorbital Filler Injection

Dermal Filler · Rejuvenation

Enrolled (actual)
11
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcome: Primary: Volumetric Change in Infraorbital Treatment Baseline to Each Post-intervention Timepoint Day 14, Day 30, and Day 90 — -0.026; -0.065; -0.108 cc

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Juvederm Volbella XC hyaluronic acid dermal filler injection (Procedure)
Age
Adult, Older Adult · 22+ yrs
Sex
Female
Sponsor
University of Pennsylvania
Primary completion
Apr 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Volumetric Change in Infraorbital Treatment Baseline to Each Post-intervention Timepoint Day 14, Day 30, and Day 90
-0.026; -0.065; -0.108
SECONDARY
Patient Satisfaction With Validated the Questionnaire FACE-Q
46.4; 59.9; 61.4; 66.6; 63.4; 55.4

Summary

The goal of this clinical trial is to measure the facial volumetric changes over time in patients injected with hyaluronic acid dermal filler (Juvéderm Volbella XC) in the infraorbital (under eye) region. Participants will be injected with Juvéderm Volbella XC filler and asked to return for 3D photography at 2 weeks, 1 month, and 3 months post-injection.

Eligibility Criteria

Inclusion Criteria

  • female
  • age 22 to 65
  • interested in filler injections to reduce undereye volume loss

Exclusion Criteria

  • male
  • age 65
  • prior undereye filler
  • filler/neurotoxin injection within the past 12 months
  • prior facial cosmetic surgery
  • prior facial trauma
  • planned dental work within next 2 weeks
  • travel 1 week prior or 2 weeks after injection
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05694286). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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