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N/A N=60 Randomized Double-blind Treatment

Effect of Cryotherapy on Post-endodontic Pain

Cryotherapy

Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Dec 2024
Primary outcome: Primary: The Level of Post-endodontic Pain — 1.85; 2.15; 3.65 score on a scale — p=0.986

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cryotherapy (Procedure); Occlusal reduction (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Gulf Medical University
Primary completion
Sep 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
The Level of Post-endodontic Pain
0.10; 0.05; 0.25 0.424
PRIMARY
The Level of Post-endodontic Pain
0.10; 0.05; 0.25 0.424
PRIMARY
The Level of Post-endodontic Pain
0.10; 0.05; 0.25 0.424
PRIMARY
The Level of Post-endodontic Pain
0.10; 0.05; 0.25 0.424

Summary

The goal of this clinical trial is to compare Cryotherapy with occlusal reduction in the reduction of post-endodontic pain in molars with symptomatic apical periodontitis. The main question it aims to answer is: Is there is a difference in post-endodontic pain intensity following cryotherapy or occlusal reduction in patients with symptomatic apical periodontitis on mandibular first molars? Participants will undergo root canal treatment including cryotherapy or post-operative occlusal reduction. Researchers will compare [Cryotherapy, occlusal reduction, and no intervention] to see the intensity of post-endodontic pain.

Eligibility Criteria

Inclusion Criteria

  • Age: 18-70 years
  • A patient diagnosed with symptomatic irreversible pulpitis/acute apical periodontitis
  • require endodontic therapy
  • Mandibular first molars that are diagnosed with symptomatic irreversible pulpitis/acute apical periodontitis
  • Healthy patients without systemic disease
  • Permanent mature first mandibular molars

Exclusion Criteria

  • Medically compromised patients
  • Pregnant patients
  • Teeth with incomplete apex formation
  • Teeth with calcified canals
  • Periapical abscess
  • Patients on antibiotic therapy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05722704). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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