N/A
Completed N=46
Optimization of Adaptive Text Messages for Cancer Survivors (OATS II)
Colon Adenocarcinoma · Colorectal Cancer · rectal adenocarcinoma
Source: ClinicalTrials.gov NCT05746195 ↗
Enrolled (actual)
46
Serious AEs
2.2%
Results posted
Jan 2026
Primary outcomePrimary: Median Percentage of Text Messages That Participants Responded to That Asked for a Reply — 96 percentage of text messages
Summary
This clinical trial evaluates whether an adaptive text-message intervention is useful in helping survivors of colorectal cancers (CRC) eat more whole grain foods and less refined grain foods. Most CRC survivors don't achieve the recommended intakes of whole grains or fiber, even though there is strong evidence that a high-fiber diet rich in whole grains lowers the risk of death from CRC. Dietary interventions are a promising approach for reducing death from CRC, and text message interventions specifically are a promising tool for reaching diverse populations. This trial evaluates a text-message based dietary intervention that continuously adapts message content to be specifically tailored for the participant for increasing whole grain consumption.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Median Percentage of Text Messages That Participants Responded to That Asked for a Reply |
96 | — |
| PRIMARY Overall Median Score on the System Usability Scale (SUS) |
72.5 | — |
| PRIMARY Overall Score on the Acceptability of Intervention Measure (AIM) |
4 | — |
| PRIMARY Overall Score on the Intervention Appropriateness Measure (IAM) |
4 | — |
| PRIMARY Feasibility of Intervention Measure (FIM) |
4 | — |
| SECONDARY Change in Percent of Grains That Are Whole Reported on the Food Frequency Questionnaire (FFQ) |
22.1 | — |
| SECONDARY Change in Mean Total Daily Fiber Intake (Grams Per Day (g/d)) Reported on the Food Frequency Questionnaire (FFQ) |
4.3 | — |
Eligibility Criteria
Inclusion Criteria
- Age > 18 years.
- Subject has provided informed consent.
- Diagnosis of colon or rectal adenocarcinoma.
- Not on active treatment at the time of screening and not expected to receive active anticancer therapy (e.g., surgery, radiation, chemotherapy) during the study period.
- At least 6 weeks since a major surgery and fully recovered.
- Owns a mobile phone and is willing and able to receive and send text messages.
- Able to speak/read English or Spanish.
- Based on a screening survey, eat grains and =<50% of total grains are whole grains.
Exclusion Criteria
- Does not meet any of the above inclusion criteria.
Data sourced from ClinicalTrials.gov (NCT05746195). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.