N/A N=42 Basic Science

Durability of Two Skin Barrier Protectants (SBP)

Skin Hydration in Healthy Volunteers

Bottom Line

View on ClinicalTrials.gov: NCT05756348 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2024

Primary outcome: Primary: Duration — 36.71; 36.31; 7.95; 20.98 arbitrary units

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Marathon® XL No Sting Cyanoacrylate Skin Protectant and 3M™ Cavilon™ Advanced Skin Protectant (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Medline Industries
Primary completion: Nov 2022

Outcome Measures

Outcome	Result	p-value
PRIMARY Duration	36.71; 36.31; 7.95; 20.98; 9.58; 17.00	—
PRIMARY Durability	3.00; 4.49; 1.37; 2.70; -0.59; 2.53	—
SECONDARY Participant Feedback 2	3; 10; 11; 18; 0; 8	—
SECONDARY Participant Feedback	36; 6; 37; 5; 10; 32	—
SECONDARY Participant Feedback - Product Preference	7; 35	—

Summary

The current study will evaluate the duration of wear and durability of two commercially available SBPs: Medline Marathon® XL (extra long) No Sting Cyanoacrylate Skin Protectant (henceforth referred to as "Marathon®") and 3M™ Cavilon™ Advanced Skin Protectant (henceforth referred to as "Cavilon™").

Eligibility Criteria

Inclusion Criteria

Individuals ≥ 18 years of age

Exclusion Criteria

Individuals have skin conditions that might interfere with Corneometer® measurements, including rash, irritation, sunburn, tattoo, birthmark, any other dermal irregularities on the left or right volar forearm or inner elbow.
Individuals have excessive hair on the left or right volar forearm or inner elbow as determined by study personnel.
Individuals have a self-reported allergy/sensitivity to ingredients present in either of the SBPs, components of the soap used for bathing, or the exam gloves and non-toxic marker used in the study.
Individuals are pregnant.
Individuals whose self-reported activities may affect friction on one arm more than the other (eg, sports like tennis or holding a baby where one arm is used more routinely than the other).
Individuals who are able to identify the manufacturer of the SBPs included in the study.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05756348). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.