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N/A N=272 Randomized Double-blind Supportive Care

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery

Coronary Artery Diseases · Valvular Heart Diseases

Enrolled (actual)
272
Serious AEs
Results posted
Sep 2025
Primary outcome: Primary: Depression — 0.31; 0.42 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Reiki/manual therapy (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The Cleveland Clinic
Primary completion
Sep 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Depression
0.29; 0.40
PRIMARY
Depression
0.29; 0.40
PRIMARY
Anxiety
0.60; 0.78
PRIMARY
Anxiety
0.60; 0.78
PRIMARY
Sleep
42.7; 46.7
PRIMARY
Sleep
42.7; 46.7
PRIMARY
Pain Level, Mean Score
2.5; 2.5
PRIMARY
Pain Level, Median Score
1.0; 1.5
PRIMARY
Hospital Length of Stay, Days - Mean (Standard Deviation)
6.3; 6.5
PRIMARY
New-onset Postoperative Atrial Fibrillation Complication
46; 51
PRIMARY
All-cause 30-day Hospital Readmission
4; 11
PRIMARY
Total Opioid IV Narcotic Burden (Mean) in mg
20; 18.4
PRIMARY
Total Oral Narcotic Burden (Mean) in Milligarms
60; 55.3
SECONDARY
Number of Participants With Hospital Re-admission Within 30 Days
4; 11

Summary

Reiki is an energy-based healing therapy using light touch. Manual therapy is a technique using light effleurage. These complimentary healing services are utilized to promote relaxation, sleep, improve emotions, and decrease pain; however, more research is required since sample sizes in the literature were small, subjects were generally healthy (not hospitalized), and subjects had multiple medical backgrounds. Only 1 study focused on cardiac surgery patients. We aim to learn if Reiki and manual therapy enhances postoperative clinical outcomes for patients after first time coronary artery bypass graft (CABG) and/or cardiac valve surgery. A randomized, controlled non-blinded study will enroll a sample of a minimum of 272 patient (136 per group), based on a power analysis using the primary outcome. The intervention group will receive usual care plus Reiki and manual therapy, with Reiki delivered first. Total therapies time is 20 minutes. Reiki and manual therapy will be delivered for 3 consecutive days beginning on the day after endotracheal tube removal. The usual care group will receive 20 minutes of uninterrupted rest, which is part of usual postoperative care. Outcomes are depression, anxiety, pain, night time sleep, new onset atrial fibrillation, hospital length of stay, all-cause 30-day hospital readmissions, narcotic drug burden and post-operative complications.

Eligibility Criteria

Inclusion Criteria

  • Over 18 years of age
  • Speaks English language and capable of reading and hearing
  • Up to 4 "To Come In" patients enrolled per day (2 standard care and 2 intervention group)
  • Arrive for surgery from outpatient (home) environment
  • Scheduled for surgery (arrives in "To Come In" area) on Monday and Tuesday.
  • Lives in one of 6 counties of North East Ohio to ensure access post-discharge hospitalization

Exclusion Criteria

  • History of dementia, cognitive decline, Down's syndrome or other neurologic, psychological or congenital deficiency that impacts ability to make decisions about enrollment
  • Severe sight and hearing impairment despite assistive devices
  • Cardiac surgery on a Wednesday, Thursday or Friday
  • Treated in the hospital prior to the day of surgery
  • Prolonged intubation (over 48 hours), or reinsertion of an endotracheal tube during or before the intervention is initiated (will result in intervention withdrawal)
  • Sedated due to new onset delirium.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05853250). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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