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N/A N=34,960

Study of Progression to Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Incidence/Management and Treatment

Lung Diseases, Interstitial

Enrolled (actual)
34,960
Serious AEs
Results posted
Sep 2024
Primary outcome: Primary: Incidence Probability of Progression to Pulmonary Fibrosing-Interstitial Lung Disease (PF-ILDs) — 0.147; 0.249; 0.334; 0.395 Cumulative incidence probability

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Boehringer Ingelheim
Primary completion
May 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Incidence Probability of Progression to Pulmonary Fibrosing-Interstitial Lung Disease (PF-ILDs)
0.147; 0.249; 0.334; 0.395
SECONDARY
Number of Patients With Treatment of Interest During Follow-up Period
49; 499; 30; 200; 225; 201
SECONDARY
Number of Patients With Management of Interest During Follow-up Period
1641; 0; 9520

Summary

The primary objective for this trial is to investigate the incidence probability of progression to Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs) in patients with fibrosing ILD other than Idiopathic Pulmonary Fibrosis (IPF) in real-world setting in Japan. The secondary objective is to investigate the characteristics of procedures for management and treatment in patients with fibrosing ILD other than IPF in real-world setting in Japan.

Eligibility Criteria

Inclusion Criteria

  • Patients diagnosed with at least two fibrosing Interstitial Lung Disease (ILD) codes on different dates in the patient identification period
  • Patients aged 18 years and older on the index date
  • Patients for whom data for the 12 months prior to the index date can be extracted as baseline data

Exclusion Criteria

  • Patients grouped into the underlying disease of Idiopathic Pulmonary Fibrosis (IPF)
  • Patients who have met PF-ILD progression criteria during the baseline period
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05875532). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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