N/A
Completed N=9
Behavioral Economics and Communication
Problem Behavior
Source: ClinicalTrials.gov NCT05918393 ↗
Enrolled (actual)
9
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcomePrimary: Averge of Aappropriate Communication Responses — 3.33 direct observation of 5-min sessions
Summary
This project examines mechanisms to address two significant challenges present in communication-based behavioral interventions for individuals with autism and comorbid severe destructive behavior (SDB): (a) inflexible communication responding and (b) reemergence of severe destructive behavior when challenges to treatment integrity occur. Achieving the proposed aims will advance clinical practice related to the treatment of SDB and generalization of treatment effects to mitigate against the resurgence of SDB
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Averge of Aappropriate Communication Responses |
3.33 | — |
| PRIMARY Average of Problem Behavior Responses |
0.48 | — |
Eligibility Criteria
Inclusion Criteria
- between 5 and 13 years of age
- documented diagnosis of autism spectrum disorder (ASD) or a diagnosis confirmed based on the relevant cutoff score of the Autism Diagnostic Observation Scale (ADOS-2)
- referred for clinical assessment and treatment of severe destructive behavior (SDB; e.g., SIB, aggression) that (a) poses a serious danger to self, others, or the environment, and (b) interferes with the child receiving an appropriate education
- children whose functional analysis results indicate that SDB is maintained by social-negative or social-positive reinforcement will be admitted to this investigation.
Exclusion Criteria
- severity of their SDB prohibits exposure to baseline conditions
- undergoing changes in their medication regimen
- results of the functional analyses indicate that their SDB is maintained by automatic reinforcement
Data sourced from ClinicalTrials.gov (NCT05918393). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.