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N/A N=251 Randomized Single-blind Prevention

Nicotine and Tobacco Message Framing Among LGBT Young Adults

Tobacco-Related Carcinoma

Enrolled (actual)
251
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Visual Attention - Dwell Time — 1871.00; 1881.01; 1695.21; 1603.15 milliseconds

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Health communications (Behavioral)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Ohio State University Comprehensive Cancer Center
Primary completion
Jan 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Attention - Dwell Time
1871.00; 1881.01; 1695.21; 1603.15; 317.90; 338.23
PRIMARY
Visual Attention - Time to First Fixation
890.45; 929.25; 3525.47; 3494.96; 1919.12; 1997.02
PRIMARY
Perceived Message Effectiveness - Message Perceptions
3.68; 3.7
PRIMARY
Perceived Message Effectiveness - Effects Perceptions
3.64; 3.80; 3.49; 3.69
PRIMARY
Change in Behavioral Intentions
.20; .36; .44; .30
PRIMARY
Behavioral Intentions: Quitting Smoking
22; 25
PRIMARY
Behavioral Intentions to Quit Vaping
29; 31
SECONDARY
Reactance
2.11; 2.07
SECONDARY
Ad Relevance
3.65; 3.64
SECONDARY
Liking
3.82; 4.04
SECONDARY
Attitudes
2.78; 2.94; 2.81; 2.90
SECONDARY
Response Efficacy
2.07; 1.93; 3.48; 3.43; 1.53; 1.51
SECONDARY
Qualitative Recall of Health Messages
81; 79

Summary

This trial refines and evaluates how cultural targeting influences the effectiveness of anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use). Polytobacco use is associated with nicotine dependence and tobacco use into adulthood, and is disproportionately high among LGBT young adults. This trial seeks to determine how cultural targeting can be applied to communicate polytobacco use risk to at-risk LGBT young adults.

Eligibility Criteria

Inclusion Criteria

  • Speaks English fluently
  • Self-identifies as lesbian, gay, bisexual, transgender, queer, or another non- heterosexual orientation or non-binary gender identity
  • Ever used e-cigarettes AND combustible cigarettes
  • Currently uses e-cigarettes, combustible cigarettes, or both e-cigarettes and combustible cigarettes
  • Resides in the United States
  • Access to a laptop or desktop computer with a camera for virtual eye-tracking

Exclusion Criteria

  • Glaucoma
  • Cataracts
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05972941). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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