N/A Completed N=30 Randomized Treatment

Comparing the Effects of Upper and Lower Body Resistance Training on Pain Sensitivity

Healthy

Source: ClinicalTrials.gov NCT05985382 ↗

Enrolled (actual)

Serious AEs

—

Results posted

Mar 2025

Primary outcomePrimary: Lower Body Resistance Exercise — 594.10; 572.54 kilopascals

Summary

Resistance exercise may immediately lessen the perception of pain. The purpose of this study is compare the effects of an upper body exercise to a lower body exercise on the perception of pain (pressure pain threshold).

Outcome Measures

Outcome	Result	p-value
PRIMARY Lower Body Resistance Exercise	594.10; 572.54	—
SECONDARY Heat Pain Threshold	43.75; 43.56	—

Eligibility Criteria

Inclusion Criteria

pain free

Exclusion Criteria

non-English speaking
regular use of prescription pain medications
current or history of chronic pain condition
currently taking blood-thinning medication
any blood clotting disorder
medical conditions known to affect sensation, such as: uncontrolled diabetes or neurological conditions
any contraindication to the application of ice, including: uncontrolled hypertension, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise
not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
surgery, injury, or fracture within the past 6 months
unable to perform exercise portions of the study
unable to attend three sessions
pregnant

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05985382). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.