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N/A N=65 Randomized Basic Science

Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases

Cigarette Smoking · Nicotine Vaping

Enrolled (actual)
65
Serious AEs
0.0%
Results posted
Feb 2026
Primary outcome: Primary: Percent Budget Spent on Illegal Cigarettes Across Policy Conditions — 40.78; 38.41; 12.14; 9.64 percentage of budget spent

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Promotion factors (Behavioral); Mitigation strategies (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
Virginia Polytechnic Institute and State University
Primary completion
Feb 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Percent Budget Spent on Illegal Cigarettes Across Policy Conditions
40.78; 38.41; 12.14; 9.64; 71.20; 65.18
PRIMARY
Percent Budget Spent on Legal Cigarettes Across Policy Conditions
37.97; 29.72; 57.30; 47.73; 4.32; 0.89
PRIMARY
Percent Budget Spent on E-cigarettes Across Policy Conditions
10.01; 23.06; 20.16; 27.15; 11.49; 24.06
PRIMARY
Percent Budget Spent on Nicotine Replacement Therapy Across Policy Conditions
2.00; 3.67; 3.11; 4.56; 3.46; 4.38
PRIMARY
Percent Budget Spent on Oral Nicotine/Tobacco Across Policy Conditions
0.85; 0.12; 0.69; 0.89; 1.08; 0.21

Summary

This study will investigate the effects of promotion factors and mitigation strategies on legal and illegal tobacco purchases for different tobacco-user types.

Eligibility Criteria

Inclusion Criteria

  • Provide informed consent
  • Be at least 21 years of age or older
  • Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm)
  • Stable tobacco use patterns for at least two months

For exclusive cigarette smokers:

  • Smoke at least 10 cigarettes daily and do not use NVPs regularly (no more than 9 times in the last month).
  • For dual cigarette/NVP users:
  • Smoke at least 10 cigarettes daily and use NVPs at least 3 times in a week (report use of closed nicotine salt system)

Exclusion criteria

  • Have plans to move out of the area
  • Have a serious or unstable physical or mental health condition
  • Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement
  • Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study
  • Being pregnant or lactating
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06001840). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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