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N/A N=97 Randomized Screening

Assessing Social Determinants of Health to Increase Cancer Screening

Lung Cancer

Enrolled (actual)
97
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Lung Cancer Screening Uptake — 1; 5 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Social determinants of health screening assessment and referral process (Behavioral); Current practice - Community-based lunch cancer screening (LungTalk) (Behavioral)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
Hackensack Meridian Health
Primary completion
Aug 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Lung Cancer Screening Uptake
1; 5
SECONDARY
Health Literacy
10; 10
SECONDARY
Health Literacy
10; 10
SECONDARY
Medical Mistrust
10; 5
SECONDARY
Medical Mistrust
10; 5
SECONDARY
Perceived Smoking-Related Stigma
21; 20
SECONDARY
Perceived Smoking-Related Stigma
21; 20
SECONDARY
Lung Cancer Fatalism
1; 2
SECONDARY
Lung Cancer Fatalism
1; 2
SECONDARY
Knowledge of Lung Cancer and Lung Screening
5; 3
SECONDARY
Knowledge of Lung Cancer and Lung Screening
5; 3
SECONDARY
Perceived Barriers to Lung Cancer Screening Scale
31.5; 31.5
SECONDARY
Perceived Barriers to Lung Cancer Screening Scale
31.5; 31.5
SECONDARY
Stage of Adoption for Decision-Making About Lung Screening
27; 34
SECONDARY
Stage of Adoption for Decision-Making About Lung Screening
27; 34

Summary

A multilevel lung screening intervention that pairs Social Determinants of Health (SDoH) screening and referral with a tailored health communication and decision support tool for lung screening has the potential to significantly impact lung screening uptake among at-risk individuals in the community, particularly among those who face barriers related to SDoH. In addition, findings will advance the understanding of effective strategies for improving lung screening and prevention efforts in non-traditional settings, with the ultimate goal of reducing the burden of lung cancer. As ways to support the realization of the public health benefit of lung cancer screening are considered, multiple strategies and venues to reach, and intervene, with screening-eligible is key. The goal of this study is to compare the effectiveness of a community-based lung screening educational tool paired with a social determinants of health (SDoH) screening assessment and referral process compared to a community-based lung cancer screening (LCS) educational tool alone as part of community outreach activities to improve (a) LCS rates (primary outcome); (b) intention to screen; and (c) individual-level potential drivers of LCS (health literacy, mistrust, stigma, fatalism, knowledge, health beliefs). It is hypothesized that providing SDoH screening and referral will result in higher levels of LCS, forward movement of intention to screen, and improved individual-level drivers of LCS.

Eligibility Criteria

Inclusion Criteria

  • Aged 50 years to 80 years
  • Currently smoke or quit smoking within the past 15 years
  • 20 pack-year smoking history
  • Has never had lung cancer screening
  • Able to provide informed consent
  • Able to speak and understand English

Exclusion Criteria

  • Diagnosed with lung cancer
  • Has a history of having a lung cancer screening scan
  • Unable to speak and understand English
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06052449). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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