N/A
N=20
Accommodative Behaviors in Multifocal Contact Lenses
Accommodation Disorder
Bottom Line
View on ClinicalTrials.gov: NCT06064617 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Objective Accommodative Response (in Diopters) on the Grand Seiko Autorefractor at 2.5 Diopters (40 cm) — 1.20; 1.03 Diopters
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Center-Near (+2.50D) Coopervision Biofinity Multifocal Contact Lens (Device); Center Distance (+2.50 D) Coopervision Biofinity Multifocal Contact Lens (Device)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Ohio State University
- Primary completion
- Apr 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Objective Accommodative Response (in Diopters) on the Grand Seiko Autorefractor at 2.5 Diopters (40 cm) |
1.20; 1.03 | — |
| SECONDARY Accommodation (in Diopters) Measured by Monocular Estimation Method (MEM) |
0.59; 0.18 | — |
| SECONDARY Accommodation (in Diopters) Measured by Monocular Push-Up |
12.26; 10.95 | — |
| SECONDARY Accommodation (in Cycles Per Minute) Measured by Accommodative Facility |
14.05; 12.15 | — |
| SECONDARY Phoria (in Prism Diopters) Measured by Modified Thorington at Distance |
0.53; 0.23 | — |
| SECONDARY Phoria (in Prism Diopters) Measured by Modified Thorington at Near |
-1.25; 0.05 | — |
Summary
Addition lenses are often used to treat a range of eye conditions. Addition lenses are specifically used to help patients who do not have the ability to focus their eyes to see clearly up close. Eye focusing is called accommodation. Addition lenses are easy to prescribe in a pair of glasses and are often called the bifocal portion of the glasses. Addition lenses can be used for adults who have presbyopia (they cannot read up close without the aide of a bifocal) and for patients of all ages who have eye focusing problems (e.g. accommodative insufficiency, accommodative infacility, accommodative dysfunction).
Addition powers can also be put into contact lenses. Contact lenses that have addition powers in them are called multifocal contact lenses. These are often marketed for patients that are 40 and over who have presbyopia, and are prescribed to help patients see up close as well as far away in their contact lenses. Multifocal contact lenses are also used in children with nearsightedness because studies have shown that some multifocal designs can slow down the progression of nearsightedness. As stated before, addition lenses can be used to treat eye focusing problems in patients of all ages, before presbyopia. What is unclear is whether the addition power in contact lenses has the same treatment effect as an addition power in a pair of glasses when they are being used to treat eye focusing problems. This study will assess how different kinds of multifocal contact lenses (center distance or center near) will change eye focusing and eye teaming in young adult patients.
Eligibility Criteria
Inclusion Criteria
- Ages 18 to ≤ 30 years old
- Acuity of 20/25 or better in both eyes with habitual contact lens prescription
- No history of ocular disease or active ocular inflammation
- No history of ocular or refractive surgery
- No current history of rigid contact lens wear
- Astigmatism ≤1.00 D
- Free of binocular vision disorder (strabismus, amblyopia, vergence dysfunction, accommodative dysfunction)
Exclusion Criteria
- No prior or concurrent participation in myopia control or use of low dose atropine, multifocal contact lenses
- No use of any medications suspected to affect accommodation
Data sourced from ClinicalTrials.gov (NCT06064617). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.