Mode
Text Size
Log in / Sign up
N/A N=384 Randomized Single-blind Prevention

Role of Membrane Sweeping on Initiation of Labor and Vaginal Birth in Previous Cesarean Section

Vaginal Birth After Cesarean Section

Enrolled (actual)
384
Serious AEs
0.0%
Results posted
Feb 2026
Primary outcome: Primary: Number of Participants With Onset of Labor by 40 Weeks — 119; 90 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Sweeping of membranes (Procedure)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
HITEC-Institute of Medical Sciences
Primary completion
Jul 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Onset of Labor by 40 Weeks
119; 90
SECONDARY
Number of Participants Having Successful Vaginal Delivery
71; 60

Summary

In Pakistan rate of child birth through cesarean section increased from 3.2% in 1992 to 22% in 2018 .Due to increasing rates of cesarean sections and associated morbidity the investigators should focus to reduce rate of primary cesarean section as well as repeat cesarean with cephalic presentation and singleton pregnancy after previous 1 cesarean section. Therefore, all ladies who underwent previous 1 cesarean section for non-recurrent cause should be considered for vaginal birth. Though studies show that membrane sweeping does promote the onset of labor and avoid need for formal induction of labor for prolonged pregnancy but the effects of membrane sweeping in women with a prior cesarean delivery are largely unknown. This is a randomized controlled trial. Objective of the study was to determine the effect of membrane sweeping on the onset of labor, success of vaginal delivery and neonatal outcome in patients with previous one cesarean section.

Eligibility Criteria

Inclusion Criteria

  • 1. Women willing for vaginal birth after lower segment cesarean section from 37 weeks of gestation to 40 weeks.
  • Previous one caesarean section for non-recurrent cause 3. Singleton pregnancy 4. Cephalic presentation

Exclusion Criteria

  • Previous uterine rupture
  • Major degree placenta previa
  • Any medical disorder like PIH, diabetes
  • Bad obstetrics history
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06103071). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search