N/A N=6,125 Randomized Single-blind Health Services Research

Lung Cancer Screening Eligibility Assessment

Lung Cancer

Bottom Line

View on ClinicalTrials.gov: NCT06133816 ↗

Enrolled (actual)

6,125

Serious AEs

0.0%

Results posted

May 2025

Primary outcome: Primary: Full Survey Completion — 358; 381; 383; 389 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Framed Introductory Message A (Behavioral); Framed Introductory Message B (Behavioral); Framed Introductory Message C (Behavioral); Framed Tobacco Use Message A (Behavioral); Framed Tobacco Use Message B (Behavioral); Financial Incentive (Behavioral)
Age: Adult, Older Adult · 50+ yrs
Sex: All
Sponsor: Abramson Cancer Center at Penn Medicine
Primary completion: Jan 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Full Survey Completion	358; 381; 383; 389; 372; 399	—
SECONDARY Partial Survey Completion	377; 405; 394; 403; 381; 414	—

Summary

The primary purpose of this study evaluate if different messaging impacts response rates to a brief survey (i.e., the simplified eligibility tool) that is designed to estimate pack-year eligibility for lung cancer screening (LCS). This will help inform the best way to increase response rates to the tool in future intervention studies designed to increase LCS, and expand upon survey methodology in general.

Eligibility Criteria

Inclusion Criteria

meet age eligibility (50-80 years old) for LCS based on 2021 USPSTF guidelines; and
have completed at least one primary care visit at Penn Medicine in 2020-2025

Exclusion Criteria

have a documented history of lung cancer;
have a documented history of completing LCS at Penn Medicine;
are listed as not wanting to be contacted or solicited for research; or
do not otherwise meet inclusion criteria.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06133816). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.