N/A
N=58
Voice Therapy With a Semi-occluded Vocal Tract
Voice Disorders
Bottom Line
View on ClinicalTrials.gov: NCT06137131 ↗Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Oct 2024
Primary outcome: Primary: (Supra)Glottic Activity: Amplitude of Vibration — 37.7; 32.5; 28.8; 37.1 percentage
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Straw phonation in air (Behavioral); straw phonation in water (Behavioral); /u/ phonation (Behavioral)
- Age
- Pediatric, Adult · 17+ yrs
- Sex
- All
- Sponsor
- University Ghent
- Primary completion
- Mar 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY (Supra)Glottic Activity: Amplitude of Vibration |
37.7; 32.5; 28.8; 37.1; 36.7; 39.6 | — |
| PRIMARY Supraglottic Activity: Anteroposterior Compression |
2.6; 2.3; 2.9; 1.3; 1.2; 1.0 | — |
| SECONDARY Voice Quality Index 1: Dysphonia Severity Index (DSI) |
1.0; 1.3; 0.7; 1.0; 1.7; 1.2 | — |
| SECONDARY Voice Quality Index 2: Acoustic Voice Quality Index (AVQI) |
3.63; 3.69; 4.12; 3.70; 3.86; 3.12 | — |
| SECONDARY Self-report 1: Voice Handicap Index (VHI) |
9; 12; 19; 13; 7; 12 | — |
| SECONDARY Self-report 2: Vocal Tract Discomfort Scale (VTDS) |
16; 21; 25; 16; 13; 19 | — |
| SECONDARY Self-report 3: Vocal Fatigue Index (VFI) |
14; 20; 19; 15; 11; 14 | — |
Summary
1. The first objective of this research is to investigate the immediate effects of three semi-occluded vocal tract (SOVT) exercises (straw phonation in air, straw phonation in 2cm water, and straw phonation in 5cm water) on (supra)glottic activity of vocally healthy participants and patients with voice disorders (dysphonia) visualized with laryngovideostroboscopy.
Participants will receive a flexible laryngovideostroboscopy, both during normal phonation and during the specific SOVT exercise. These videos will be randomly and blindly evaluated by two experts using the Voice-Vibratory Assessment with Laryngeal Imaging (VALI) rating form (Poburka et al., 2017).
Researchers will compare the effects of these SOVT exercises on the (supra)glottic activity with the effects found in a control group producing /u/ phonation, using a randomized controlled trial.
2. The second objective of this research is to investigate the short- and long-term effects of the three SOVT therapy approaches on the (supra)glottic activity, voice quality and self-report of patients with voice disorders (dysphonia).
Participants will receive a short-term intensive therapy with the specific SOVT exercise across four weeks.
Immediately after the therapy program and at 1 and 3 months follow-up, the voice of the participants will be re-evaluated.
Eligibility Criteria
Patients:
Inclusion criteria are aged between 17 and 50 years, and diagnosed with dysphonia by an otorhinolaryngologist and SLP experienced in voice diagnostics. Exclusion criteria are previous or current participation in voice therapy, previous phonosurgical interventions, pregnancy, smoking, nasal or ear diseases, and neurological disorders.
Vocally healthy participants:
Inclusion criteria are aged between 17 and 50 years. Exclusion criteria are dagnosed with dysphonia, previous or current participation in voice therapy, previous phonosurgical interventions, pregnancy, smoking, nasal or ear diseases, and neurological disorders.
Data sourced from ClinicalTrials.gov (NCT06137131). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.