N/A
Completed N=88
PECS II vs. MTP for Analgesia After MRM
Breast Neoplasm Female · Postoperative Pain Management
Source: ClinicalTrials.gov NCT06187909 ↗
Enrolled (actual)
88
Serious AEs
1.2%
Results posted
Aug 2025
Primary outcomePrimary: Post-operative Pain Severity Assessed by VAS at Hour-4 — 1.4; 2.2 score on a scale
Summary
This randomized controlled study aims to compare the analgesic efficacy of the ultrasound-guided modified pectoral nerve block (PECS II) and the midpoint transverse process to pleura (MTP) block in female patients undergoing modified radical mastectomy (MRM). Postoperative pain intensity will be assessed using the Visual Analog Scale (VAS) over the first 24 hours, with additional evaluation of opioid consumption and complications.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Post-operative Pain Severity Assessed by VAS at Hour-4 |
1.4; 2.2 | — |
| SECONDARY Post-operative Pain Severity Assessed by VAS on Admission to Postanesthesia Care Unit (PACU), at Hour-2, Hour-8, Hour-12, Hour-18 and Hour-24. |
0.3; 0.3; 1.1; 1.4; 2.5; 3.2 | — |
| SECONDARY Time of First Rescue Analgesia |
12.8; 7.9 | — |
| SECONDARY Cumulative Post-operative Nalbuphine Consumption in the First 24 Hours |
8.3; 13.3 | — |
| SECONDARY Incidence of Postoperative Side Effects and Complications |
9; 12; 2; 8; 1; 3 | — |
Eligibility Criteria
Inclusion Criteria
- Female patients scheduled for modified radical mastectomy (MRM).
- Age between 40 and 65 years.
- American Society of Anesthesiologists (ASA) physical status I-II.
Exclusion Criteria
- Known allergy to local anesthetics.
- Coagulopathy.
- Infection at the site of injection.
- Patient refusal.
- Inability to understand or use the pain scale.
Data sourced from ClinicalTrials.gov (NCT06187909). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.