N/A
N=80
A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study
OsteoArthritis Knee
Bottom Line
View on ClinicalTrials.gov: NCT06232018 ↗Enrolled (actual)
80
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Patient Observer Scar Assessment Score (POSAS) — 20; 21 score on a scale — p=0.481
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Skin adhesive (Dermabond) (Device); skin adhesive + polyester mesh (Dermabond prineo) (Device)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Pooriwat Lertsurawat
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Observer Scar Assessment Score (POSAS) |
13; 15 | 0.228 |
| SECONDARY Patient Observer Scar Assessment Score (POSAS) |
13; 15 | 0.228 |
| SECONDARY Vancouver Scar Scale |
5; 5 | 0.421 |
| SECONDARY Wound Leakage |
23; 79 | <0.001 sig |
| SECONDARY Vancouver Scar Scale |
5; 5 | 0.421 |
Summary
The goal of this randomized controlled study is to investigate the Efficacy of Using skin adhesive (Dermabond) and skin adhesive with polyester mesh (Dermabond Prineo )for Wound Closure in Total Knee Arthroplasty, The main question it aim to answer
1 Are skin adhesive alone and with Polyester mesh in Total knee arthroplasty different in Patient satisfaction evaluated by POSAS score
Eligibility Criteria
Inclusion Criteria
- OA knee need for Total knee arthroplasty
- Age 50-80 years old
Exclusion Criteria
- Previous surgery of knee
- History of Keloid, Scar, Psoriasis at the knee
- History of contact dermatitis with skin adhesive
- Cognitive impairment
Data sourced from ClinicalTrials.gov (NCT06232018). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.