N/A
N=36
Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency
Stuttering, Adult
Bottom Line
View on ClinicalTrials.gov: NCT06278233 ↗Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Stuttered Syllables in Passage Reading (Change in the Percentage of Stuttered Syllables After 5 Days of Intervention From Baseline) — -1.41; -0.81 percentage of stuttered syllables
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Transcranial direct current stimulation (Device)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Biruni University
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Stuttered Syllables in Passage Reading (Change in the Percentage of Stuttered Syllables After 5 Days of Intervention From Baseline) |
-1.41; -0.81 | — |
| PRIMARY Stuttered Syllables in Passage Reading (Change From Baseline in Percentage of Disfluent Syllables 1 Week After Intervention) |
0.86; 0.87 | — |
| PRIMARY Stuttered Syllables in Conversation (Change in the Percentage of Stuttered Syllables After 5 Days of Intervention From Baseline) |
-0.40; 0.07 | — |
| PRIMARY Stuttered Syllables in Conversation (Change From Baseline in Percentage of Disfluent Syllables 1 Week After Intervention) |
-0.69; 0.16 | — |
| SECONDARY Change in Stuttering Severity Instrument (SSI-IV) Scores After 5 Days of Intervention From Baseline |
-1.94; -1.76 | — |
| SECONDARY Change From Baseline in Stuttering Severity Instrument (SSI-IV) Scores 1 Week After Intervention |
-3.00; -2.06 | — |
| SECONDARY Change in The Overall Assessment of the Speaker's Experience of Stuttering (OASES) Scores After 5 Days of Intervention From Baseline |
-15.56; -8.53 | — |
| SECONDARY Change From Baseline in The Overall Assessment of the Speaker's Experience of Stuttering (OASES) Scores 1 Week After Intervention |
-14.72; -14.19 | — |
Summary
It will be determined whether bihemispheric stimulation (anodal to the left IFG and cathodal to the right IFG) is used with fluency-facilitating conditions for 5 consecutive days in individuals with stuttering and whether there is a difference in terms of the effects seen in speech fluency compared to the sham condition.
Eligibility Criteria
Inclusion Criteria
- developmental stuttering
- age between 18 and 60 years
- right hand dominant
Exclusion Criteria
- history of seizures, head trauma, hearing problems, cochlear implant, intracranial metal implantation, medications that affects the central nervous system, implanted neurostimulators, cardiac pacemakers, or medication infusion devices
- any speech and language disorder other than developmental stuttering
- neurological or psychiatric disorders, brain surgery, tumours, neurodevelopmental disorders, or attention deficit hyperactivity disorder
Data sourced from ClinicalTrials.gov (NCT06278233). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.