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N/A N=115 Randomized Supportive Care

Testing a Wellness App for First Responders, Military Personnel and Veterans

Mental Health Wellness

Enrolled (actual)
115
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: PERMA-Profiler Overall Wellbeing Score — 6.99; 7.46; 6.49 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
GUIDE (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Pennsylvania
Primary completion
Oct 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
PERMA-Profiler Overall Wellbeing Score
6.99; 7.46; 6.49
PRIMARY
Patient Health Questionnaire for Depression Symptoms (PHQ-8)
5.15; 3.86; 6.29
PRIMARY
Generalized Anxiety Disorder (GAD-7)
12.53; 10.34; 13.42
PRIMARY
WHO Well-being Index (WHO-5)
57.41; 65.71; 52.95
PRIMARY
Personal Wellbeing Score (PWS)
73.04; 77.62; 62.28
PRIMARY
Difficulties in Emotion Regulation Scale Short Form (DERS-SF)
32.82; 32.06; 36.89
SECONDARY
Positive Emotion (Positive Emotion Subscale of the PERMA-Profiler)
6.65; 7.20; 5.96
SECONDARY
Social Connectedness (Engagement Subscale of PERMA-Profiler)
6.66; 6.70; 6.68
SECONDARY
Social Connectedness (Relationship Subscale of PERMA-Profiler)
7.03; 7.81; 6.14
SECONDARY
Personal Growth (Meaning Subscale of the PERMA-Profiler)
7.33; 7.86; 6.74
SECONDARY
Personal Growth (Accomplishment Subscale of the PERMA-Profiler)
7.29; 7.74; 6.95
SECONDARY
Utrecht Work Engagement Scale (UWES-17)
61.74; 62.49; 58.61
SECONDARY
Maslach Burnout Inventory (MBI) - Emotional Exhaustion
21.24; 19.06; 19.97
SECONDARY
Maslach Burnout Inventory (MBI) - Personal Accomplishment
31.38; 32.00; 30.42
SECONDARY
Maslach Burnout Inventory (MBI) - Depersonalization
8.79; 8.86; 9.13
SECONDARY
Number of Participants Still Employed
34; 35; 38
SECONDARY
Feasibility of Intervention Measure (FIM)
3.941176471; 4.078571429
SECONDARY
Acceptability of Intervention Measure (AIM)
3.757352941; 3.878571429
SECONDARY
Intervention Appropriateness Measure (IAM)
3.933823529; 4.085714286
SECONDARY
System Usability Scale (SUS)
70.07352941; 71.14285714

Summary

The purpose of the research study is to trial a smart phone application, the GUIDE App, to better understand its impact on social connectedness, personal growth and mental health/wellness among first responders, soldiers, and veterans. The research team will also investigate workplace metrics (e.g., engagement and burnout), implementation outcomes and technical merit. The investigators plan to run a three-armed randomized waitlist pilot feasibility trial with up to 150 participants.

Eligibility Criteria

Inclusion Criteria

  • Law enforcement, military personnel, or veteran.
  • Employed (part-time, full-time, self-employed).
  • Owns compatible smartphone.
  • Not paid by the GUIDE App/Nlyten Corp.
  • No previous use of GUIDE App.

Exclusion Criteria

  • Not law enforcement, military personnel, or veteran.
  • Not employed.
  • Paid by GUIDE App/Nlyten Corp.
  • Previous use of GUIDE App.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06336967). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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