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N/A N=31,303 Randomized Screening

The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale

Lung Cancer · Lung Neoplasms/Diagnosis

Enrolled (actual)
31,303
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Study 1 Primary Outcome: Count of Patients Newly Identified as Eligible for Lung Cancer Screening — 308; 635 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
MyLungHealth (Behavioral); DecisionPrecision+ (Behavioral)
Age
Adult, Older Adult · 50+ yrs
Sex
All
Sponsor
University of Utah
Primary completion
Mar 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Study 1 Primary Outcome: Count of Patients Newly Identified as Eligible for Lung Cancer Screening
308; 635
PRIMARY
Study 2 Primary Outcome: Count of Participants for Whom LDCT Was Ordered.
434; 474
SECONDARY
Study 1 Secondary Outcome: Count of Participants for Whom LDCT Eligibility Status Became Known.
925; 3,570
SECONDARY
Study 1 Secondary Outcome: Count of Participants for Whom LDCT Was Ordered.
350; 430
SECONDARY
Study 1 Secondary Outcome: Count of Participants for Whom LDCT Was Completed.
226; 275
SECONDARY
Study 2 Secondary Outcome: Count of Participants for Whom LDCT Was Completed.
290; 293

Summary

Early lung cancer screening (LCS) through low-dose computed tomography (LDCT) is crucial but underused due to various barriers, including incomplete or inaccurate patient smoking data in the electronic health record and limited time for shared decision-making. The objective of this trial is to investigate a patient-centered intervention, MyLungHealth, delivered through the patient portal. The intervention is designed to improve LCS rates through increased identification of eligible patients and informed decision making.

Eligibility Criteria

Inclusion criteria for both study 1 and study 2:

  • aged 50-79
  • a history of smoking (e.g., current or former tobacco use)
  • seen in a study primary care clinic in the 12 months preceding the start of the trial

Exclusion criteria for both study 1 and study 2:

  • >0 but < 10 pack-year smoking history or quit more than 15 years ago
  • No use of the patient portal at least once in the year preceding the start of the study
  • A lung cancer diagnosis at the start of the study
  • LDCT completed in the past 3 years
  • Another chest CT completed in the past year
  • Structured EHR data indicating LCS SDM was provided in the past 3 years
  • Exposed to the intervention during the pilot phase
  • No visit at a study clinic during the trial period when the intervention was available

Inclusion criteria for study 1:

  • a 10-19 pack-year smoking history, an unknown pack-year history, unknown quit date for patients who quit smoking, or a 0 pack-year smoking history

Inclusion criteria for study 2:

  • at least a 20 pack-year smoking history and are a current smoker or have quit within the last 15 years
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06338592). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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