N/A
Completed N=31,303
The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale
Lung Cancer · Lung Neoplasms/Diagnosis
Source: ClinicalTrials.gov NCT06338592 ↗
Enrolled (actual)
31,303
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcomePrimary: Study 1 Primary Outcome: Count of Patients Newly Identified as Eligible for Lung Cancer Screening — 308; 635 Participants
Summary
Early lung cancer screening (LCS) through low-dose computed tomography (LDCT) is crucial but underused due to various barriers, including incomplete or inaccurate patient smoking data in the electronic health record and limited time for shared decision-making. The objective of this trial is to investigate a patient-centered intervention, MyLungHealth, delivered through the patient portal. The intervention is designed to improve LCS rates through increased identification of eligible patients and informed decision making.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Study 1 Primary Outcome: Count of Patients Newly Identified as Eligible for Lung Cancer Screening |
308; 635 | — |
| PRIMARY Study 2 Primary Outcome: Count of Participants for Whom LDCT Was Ordered. |
434; 474 | — |
| SECONDARY Study 1 Secondary Outcome: Count of Participants for Whom LDCT Eligibility Status Became Known. |
925; 3,570 | — |
| SECONDARY Study 1 Secondary Outcome: Count of Participants for Whom LDCT Was Ordered. |
350; 430 | — |
| SECONDARY Study 1 Secondary Outcome: Count of Participants for Whom LDCT Was Completed. |
226; 275 | — |
| SECONDARY Study 2 Secondary Outcome: Count of Participants for Whom LDCT Was Completed. |
290; 293 | — |
Eligibility Criteria
Inclusion criteria for both study 1 and study 2:
- aged 50-79
- a history of smoking (e.g., current or former tobacco use)
- seen in a study primary care clinic in the 12 months preceding the start of the trial
Exclusion criteria for both study 1 and study 2:
- >0 but < 10 pack-year smoking history or quit more than 15 years ago
- No use of the patient portal at least once in the year preceding the start of the study
- A lung cancer diagnosis at the start of the study
- LDCT completed in the past 3 years
- Another chest CT completed in the past year
- Structured EHR data indicating LCS SDM was provided in the past 3 years
- Exposed to the intervention during the pilot phase
- No visit at a study clinic during the trial period when the intervention was available
Inclusion criteria for study 1:
- a 10-19 pack-year smoking history, an unknown pack-year history, unknown quit date for patients who quit smoking, or a 0 pack-year smoking history
Inclusion criteria for study 2:
- at least a 20 pack-year smoking history and are a current smoker or have quit within the last 15 years
Data sourced from ClinicalTrials.gov (NCT06338592). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.