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N/A Completed N=440 Randomized Basic Science

Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study

Cigarette Smoking · Nicotine Vaping
Source: ClinicalTrials.gov NCT06456671 ↗
Enrolled (actual)
440
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcomePrimary: Proportion of Budget Spent - CIGARETTES — 89.9; 44.5; 87.3; 47.4 percentage of budget spent — p=<0.001

Summary

This study will investigate the relative appeal (abuse liability) of novel tobacco products, how the appeal is modulated by relative price, user type, and how novel products may substitute for one another.

Outcome Measures

OutcomeResultp-value
PRIMARY
Proportion of Budget Spent - CIGARETTES
89.9; 44.5; 87.3; 47.4; 76.1; 45.9 <0.001 sig
SECONDARY
Alternative Product Consumption - E-CIGARETTES
40.9; 553.4; 105.1; 617.8; 128.5; 828.3
SECONDARY
Alternative Product Consumption - HTP
2.3; 4.4; 9.5; 4.9; 2.2; 3.0
SECONDARY
Alternative Product Consumption - Nicotine Pouches
0.1; 3.4; 0.9; 4.6; 0.5; 3.5
SECONDARY
Alternative Product Consumption - Nicotine Replacement Therapy
0.6; 2.8; 2.6; 4.2; 0.4; 3.7
SECONDARY
Alternative Product Consumption - Oral Tobacco Products
0.1; 1.7; 0.4; 1.3; 0.1; 1.9

Eligibility Criteria

Inclusion Criteria

  • From CA, US, or EN
  • At least 21 years old
  • Smoking daily
  • Smoking mostly or about equal amounts of factory-made cigarettes
  • Does not currently vape (for exclusive smokers only)
  • Vapes Daily (for dual users only)

Exclusion Criteria

  • There will be no additional exclusion criteria for this study.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06456671). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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