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Phase 4 N=26 Randomized Triple-blind Prevention

Impact of Astaxanthin on Cognition in Recreationally Active Females

Mental Fatigue

Enrolled (actual)
26
Serious AEs
0.0%
Results posted
May 2026
Primary outcome: Primary: Reaction Time — 402.7; 400; 426.4; 406.6 milliseconds

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Astaxanthin (Dietary_supplement); Placebo (Dietary_supplement)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
University of North Alabama
Primary completion
Nov 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Reaction Time
402.7; 400; 426.4; 406.6; 937.2; 948.0

Summary

The purpose of this study is to examine the protentional that the antioxidant Astaxanthin has on mitigating cognitive decline following mental fatigue.

Eligibility Criteria

Inclusion Criteria

  • The participant population will be healthy, recreationally active females between the ages of 18-39 without any medical conditions. To be deemed recreationally active, they must meet the World Health Organization minimum activity guidelines of completing at least 150 to 300 min moderate-intensity activity or 75-150 min of vigorous-intensity activity a week, plus muscle-strengthening activities 2 or more days a week.
  • Adult females with a stable body weight (± 5 lbs.) for 2 months
  • Adult females with a normal menstrual cycle
  • Adult females not on a low-carb, high-fat diet or intermittent fasting
  • Adult females who are not pregnant of actively attempting to become pregnant

Exclusion Criteria

-

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06460181). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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