N/A
N=32
Low-Load Blood Flow Restriction Training vs Traditional Resistance Training Exercises Following ACLR Surgery
Strength · Range of Motion · Pain-Knee · Skeletal Muscle Hypertrophy · Effusion Joint
Bottom Line
View on ClinicalTrials.gov: NCT06480032 ↗Enrolled (actual)
32
Serious AEs
—
Results posted
Aug 2025
Primary outcome: Primary: Range of Motion — 74.0625; 80.3125 Degrees
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Blood Flow Restriction band (Device)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Abasyn University Peshawar
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Range of Motion |
74.0625; 80.3125 | — |
| PRIMARY Quadricep Strength |
3.9375; .6800735 | — |
| PRIMARY Knee Pain |
2.0625; 1.9375 | — |
| PRIMARY Quadricep Size |
19.375; 18.65625 | — |
Summary
The main objective/s of the study is to compare the effectiveness of low load blood flow restriction training (LL-BFR) with traditional resistance training exercises (T-RT) at improving skeletal muscle hypertrophy, strength, Range of motion (ROM), pain and effusion in individuals who have undergone anterior cruciate ligament (ACL) reconstruction surgery.
The study involves 32 participants who meet the inclusion criteria and randomly assign to either BFR-RT group or the T-RT group. The primary outcomes measured includes skeletal muscle hypertrophy, strength, range of motion, pain, and effusion.
The intervention last for eight weeks, during which participants undergone resistance training according to their assigned group. Data collected at various time points, including post-surgery, mid-training, and post-training, to assess the effectiveness of the two training methods. The findings from this study are effective for anterior cruciate ligament reconstruction surgery (ACLR) patients in early rehabilitation and improve outcomes for individuals recovering from ACL injuries.
Eligibility Criteria
Inclusion Criteria
- Post-ACL reconstruction surgery (week 0-8)
- Both male and female
- No known history of central or peripheral neurological impairment
- Free of any cardiac, pulmonary or metabolic conditions
- Willing to participate
Exclusion Criteria
- History of deep vein thrombosis or vascular pathology in any lower limb
- Intraarticular injections into the knee in the preceding 6 months
- Rheumatoid arthritis or other significant co-morbidities
- Use of anticoagulant medications
Data sourced from ClinicalTrials.gov (NCT06480032). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.