N/A N=24

Sevoflurane Concentrations in Children

Anesthetic · Sevoflurane · Age

Bottom Line

View on ClinicalTrials.gov: NCT06510803 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2026

Primary outcome: Primary: Ratios of the Inspired to Expired Sevoflurane Concentrations During Induction of Anesthesia — 0; 0; 0.684; 0.6615 ratio

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: The washin of sevoflurane in the GE Ohmeda workstation (Drug)
Age: Pediatric · 2+ yrs
Sex: All
Sponsor: State University of New York at Buffalo
Primary completion: Oct 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Ratios of the Inspired to Expired Sevoflurane Concentrations During Induction of Anesthesia	0; 0; 0.684; 0.6615; 0.816; 0.80	—
SECONDARY Maximum Inspired Concentration at 1 Minute of Induction	7.8; 6.4	—
SECONDARY Maximum Sevoflurane Concentrations During Induction of Anesthesia	8.5; 7.2	—
SECONDARY Time to Reach 90% of the Maximum Inspired Concentration	0.5; 1.75	—

Summary

The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.

Eligibility Criteria

Inclusion Criteria

scheduled for elective surgery under general anesthesia,
American Society of Anesthesiologists physical status 1 or 2 fasted, unpremeditated

Exclusion Criteria

parents refuse consent
presence of moderate or severe cardiorespiratory disease
difficult airway
malignant hyperthermia
neuromuscular disorders
obesity
obstructive sleep apnea

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06510803). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.