N/A N=423

The Blued+ Combination HIV Prevention Pilot Study in China

Pre-Exposure Prophylaxis

Bottom Line

View on ClinicalTrials.gov: NCT06647173 ↗

Enrolled (actual)

423

Serious AEs

0.0%

Results posted

Jul 2025

Primary outcome: Primary: Feasibility of Blued+ in China — 193; 316 Participants

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: Blued+ Service Platform (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: Male
Sponsor: Emory University
Primary completion: Dec 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Feasibility of Blued+ in China	193; 316	—
PRIMARY System Usability Scale (SUS)	73.4	—

Summary

The proposed research includes a longitudinal pilot study to assess the feasibility and acceptability of Blued+. This combination HIV prevention intervention will integrate a combination package of HIV prevention services into Blued, a gay dating App, for men who have sex with men (MSM) in China. Despite high HIV incidence among MSM, HIV prevention interventions such as pre-exposure prophylaxis (PrEP) use remains low in China. If the HIV prevention intervention services provided through the Blued+ App prove feasible and acceptable, the pilot test will facilitate the design of a larger study of intervention efficacy. The study population will be self-reported HIV-negative Blued users who are 18 years of age or greater, were assigned a male sex at birth, report having anal sex with a man in the last 6 months, eligible for PrEP according to China's consensus statement, and reside in metropolitan Beijing or Chengdu, China.

Eligibility Criteria

Inclusion Criteria

Registered Blued app user
≥18 years of age
Male sex at birth
Self-report anal sex with a man in the last 6 months
HIV-negative or unknown HIV status
Behaviorally eligible for PrEP per published China guidance
Able to complete study instruments in Mandarin Chinese
Resident of the metropolitan area of Beijing or Chengdu, China
Eligible for PrEP based on China's consensus statement
Additional Inclusion criteria apply for PrEP

Exclusion Criteria

Not a registered Blued app user
<18 years of age
Not male sex at birth
Does not report anal sex with a man in the last 6 months
Has previously tested positive for HIV
Not eligible for PrEP per published China guidance
Unable to complete study instruments in Mandarin Chinese
Not a resident of the metropolitan area of Beijing or Chengdu, China
Currently enrolled in another HIV prevention study
Evidence of fraudulent participation, such as a duplicate IP address, multiple screening attempts, duplicate emails, etc.
Additional Inclusion criteria apply for PrEP

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06647173). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.