N/A
Completed N=423
The Blued+ Combination HIV Prevention Pilot Study in China
Pre-Exposure Prophylaxis
Source: ClinicalTrials.gov NCT06647173 ↗
Enrolled (actual)
423
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcomePrimary: Feasibility of Blued+ in China — 193; 316 Participants
Summary
The proposed research includes a longitudinal pilot study to assess the feasibility and acceptability of Blued+. This combination HIV prevention intervention will integrate a combination package of HIV prevention services into Blued, a gay dating App, for men who have sex with men (MSM) in China.
Despite high HIV incidence among MSM, HIV prevention interventions such as pre-exposure prophylaxis (PrEP) use remains low in China. If the HIV prevention intervention services provided through the Blued+ App prove feasible and acceptable, the pilot test will facilitate the design of a larger study of intervention efficacy.
The study population will be self-reported HIV-negative Blued users who are 18 years of age or greater, were assigned a male sex at birth, report having anal sex with a man in the last 6 months, eligible for PrEP according to China's consensus statement, and reside in metropolitan Beijing or Chengdu, China.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility of Blued+ in China |
193; 316 | — |
| PRIMARY System Usability Scale (SUS) |
73.4 | — |
Eligibility Criteria
Inclusion Criteria
- Registered Blued app user
- ≥18 years of age
- Male sex at birth
- Self-report anal sex with a man in the last 6 months
- HIV-negative or unknown HIV status
- Behaviorally eligible for PrEP per published China guidance
- Able to complete study instruments in Mandarin Chinese
- Resident of the metropolitan area of Beijing or Chengdu, China
- Eligible for PrEP based on China's consensus statement
- Additional Inclusion criteria apply for PrEP
Exclusion Criteria
- Not a registered Blued app user
- <18 years of age
- Not male sex at birth
- Does not report anal sex with a man in the last 6 months
- Has previously tested positive for HIV
- Not eligible for PrEP per published China guidance
- Unable to complete study instruments in Mandarin Chinese
- Not a resident of the metropolitan area of Beijing or Chengdu, China
- Currently enrolled in another HIV prevention study
- Evidence of fraudulent participation, such as a duplicate IP address, multiple screening attempts, duplicate emails, etc.
- Additional Inclusion criteria apply for PrEP
Data sourced from ClinicalTrials.gov (NCT06647173). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.