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N/A N=200 Randomized Double-blind Diagnostic

Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement

Intubation; Difficult or Failed

Enrolled (actual)
200
Serious AEs
0.0%
Results posted
May 2026
Primary outcome: Primary: Correct Classification of Endotracheal Tube Position — 65; 66; 64 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Tracheal Ultrasound (Diagnostic_test); Lung Ultrasound (Diagnostic_test); Diaphragm Ultrasound (Diagnostic_test)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Marmara University Pendik Training and Research Hospital
Primary completion
Jun 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Correct Classification of Endotracheal Tube Position
65; 66; 64
SECONDARY
Endotracheal Intubation Confirmation Time
4.6; 9.4; 13.4
SECONDARY
Sonographer Confidence
4.68; 4.65; 4.65

Summary

This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation. Two sonographers will independently verify the accuracy of the intubation site using the assigned intubation method (tracheal, lung-sliding, or diaphragm) according to the randomization sequence. Each sonographer will be blinded to the other verification methods (physical examination, end-tidal carbon dioxide) being used. The study's primary objective is to compare the diagnostic accuracy of different intubation techniques.

Eligibility Criteria

Inclusion Criteria

  • Patients in the emergency department who require endotracheal intubation (ETI) based on the decision of the primary physician and are intubated using the rapid sequence intubation method.
  • Patients aged >18 years will be included in the study.

Exclusion Criteria

  • Pregnant patients.
  • Patients with a history of neck or chest surgery that may interfere with ultrasound evaluation.
  • Patients with cervical spine disease or a history of surgery that could affect diaphragmatic movement.
  • Patients diagnosed conditions such as pneumothorax that could affect lung ultrasound results, or those in whom pneumothorax is detected upon further evaluation,
  • Patients who, after being enrolled, withdraw consent either personally or through a relative.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06656546). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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