N/A
N=60
A Study to Evaluate the Effects of a Dietary Supplement on Children's Health and Development Outcomes.
Height · Cognitive Function · Weight Gain
Bottom Line
View on ClinicalTrials.gov: NCT06704178 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Change Mean Percentile Score in Double Trouble — 168.55; 129.46 percent change from baseline — p=0.488445
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- NuBest Tall Growth Protein Powder (Dietary_supplement); Placebo Powder (Dietary_supplement)
- Age
- Pediatric · 10+ yrs
- Sex
- All
- Sponsor
- NuBest
- Primary completion
- Feb 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change Mean Percentile Score in Double Trouble |
168.55; 129.46 | 0.488445 |
| PRIMARY IChange Mean Percentile Score in Feature Match |
34.60; 58.20 | 0.98317 |
| PRIMARY Change Mean Percentile Score in Grammatical Reasoning |
56.59; 88.39 | 0.98317 |
| PRIMARY Change Mean Percentile Score in Digit Span |
28.02; 19.69 | 0.919209 |
| PRIMARY Change Mean Percentile Score in Token Search |
6.26; 40.20 | 0.919209 |
| SECONDARY Increase in Height |
0.89; 1.16; 3.25; 1.67; 3.47; 3.49 | 0.954882 |
| SECONDARY Changes in Weight |
4.67; 4.50; 5.52; 2.29; 7.53; 4.65 | 0.483382 |
| SECONDARY Changes in Overall Health as Reported by Parents |
0.45; 0.19; 1.22; 6.73; -0.51; 14.42 | 0.999216 |
| SECONDARY Change in Parents' Perception of the Child's Health in the Future. |
16.99; 3.53; 19.87; 7.33; 19.55; 9.78 | 0.999851 |
| SECONDARY Parents' Perception of the Change in Child's Health Compared to One Month Ago. |
12.82; 8.01; 18.27; 17.33; 20.19; 25.00 | 0.999851 |
| SECONDARY Change in Child's Energy Levels as Reported by Parents |
9.17; 11.47; 5.83; 13.20; 11.86; 26.88 | 0.999835 |
| SECONDARY Changes in Limitations When Completing High-Intensity Activity |
8.33; 3.85; 12.18; 0.00; 6.41; -13.77 | 0.999851 |
| SECONDARY Changes in Limitations When Completing Moderate-Intensity Activity |
0.64; 8.33; 0.64; 4.67; -3.21; -9.42 | 0.999732 |
| SECONDARY Changes in Limitations When Moving Around |
7.69; 14.10; 7.69; 6.67; 3.85; -1.45 | 0.999851 |
| SECONDARY Changes in Limitations When Walking 100 Meters or Climbing a Flight of Stairs |
-0.96; 6.41; 2.88; -1.33; -2.88; -1.45 | 0.999387 |
| SECONDARY Change in Limitations When Bending, Lifting, or Stooping. |
5.77; 6.41; 3.85; 0.67; -3.85; -1.45 | 0.999975 |
| SECONDARY Change in Limitations in the Kind of Schoolwork or Activities Undertaken. |
5.77; -0.96; 5.77; -4.00; 1.92; -5.43 | 0.981906 |
| SECONDARY Change in Limitations in the Amount of Time Spent Completing Schoolwork or Activities. |
19.23; -5.13; 0.00; -3.00; 7.69; -9.78 | 0.55783 |
| SECONDARY Change in Limitations During the Completion of Schoolwork or Activities. |
5.77; -0.64; 9.62; -2.00; 3.85; -13.04 | 0.795476 |
| SECONDARY Change in Parents' Perception of Child's Health Compared to Other Children. |
-1.92; 1.60; 2.56; -4.00; -16.67; 1.45 | 0.995367 |
| SECONDARY Change in Parents' Perception of Child's Immunity |
-5.77; 18.59; -11.86; 1.33; -8.01; 12.68 | 0.882016 |
| SECONDARY Change in Parents' Worry About Child's Health |
7.37; -9.29; 12.18; 1.33; 2.24; 1.45 | 0.999975 |
| SECONDARY Change in Parent-reported Frequency of Child's Stomach Aches |
-4.49; -9.62; -7.69; -11.00; -10.26; -7.97 | 0.999851 |
| SECONDARY Change in Parent-reported Frequency of Child's Difficulty Going to the Toilet |
-6.79; -7.05; -10.19; -7.00; -18.21; -11.96 | >0.999999 |
| SECONDARY Change Mean Percentile Score in Double Trouble - NuBest Group Only (Within-Group Analysis) |
28; 48.67 | 0.0003 sig |
| SECONDARY Change Mean Percentile Score in Feature Match - NuBest Group Only (Within-Group Analysis) |
39.58; 45.75 | 0.2698 |
| SECONDARY Change Mean Percentile Score in Grammatical Reasoning Match - NuBest Group Only (Within-Group Analysis) |
47.42; 56.54 | 0.2698 |
| SECONDARY Change Mean Percentile Score in Digit Span - NuBest Group Only (Within-Group Analysis) |
42.29; 50.88 | 0.2137 |
| SECONDARY Change Mean Percentile Score in Token Search - NuBest Group Only (Within-Group Analysis) |
53.17; 53.04 | 0.8639 |
| SECONDARY Change Mean Percentile Score in Double Trouble - Placebo Group Only (Within-Group Analysis) |
33.73; 49.62 | 0.239 |
| SECONDARY Change Mean Percentile Score in Feature Match - Placebo Group Only (Within-Group Analysis) |
40.81; 45.29 | 0.6088 |
| SECONDARY Change Mean Percentile Score in Grammatical Reasoning - Placebo Group Only (Within-Group Analysis) |
47.05; 54.33 | 0.5738 |
| SECONDARY Change Mean Percentile Score in Digit Span - Placebo Group Only (Within-Group Analysis) |
52.57; 57.62 | 0.6088 |
| SECONDARY Change Mean Percentile Score in Token Search - Placebo Group Only (Within-Group Analysis) |
48.62; 55.62 | 0.4942 |
| SECONDARY Increase in Height - Nubest Group Only (Within-Group Analysis) |
61.69; 62.01; 63.33; 63.24 | 0.7419 |
| SECONDARY Increase in Height - Placebo Group Only (Within-Group Analysis) |
60.66; 62.41; 62.71; 63.05 | 0.7708 |
| SECONDARY Changes in Weight - Nubest Group Only (Within-Group Analysis) |
121.68; 126.38; 124.36; 123.82 | 0.0219 sig |
| SECONDARY Changes in Weight - Placebo Group Only (Within-Group Analysis) |
130.43; 137.92; 133.06; 128.99 | 0.0695 |
| SECONDARY Changes in Overall Health as Reported by Parents - NuBest Group Only (Within-Group Analysis) |
4.33; 4.29; 4.33; 4.25; 4.42; 4.33 | >0.9999 |
| SECONDARY Change in Parents' Perception of the Child's Health in the Future - NuBest Group Only (Within-Group Analysis) |
3.38; 3.63; 3.71; 3.67; 3.58; 3.71 | >0.9999 |
| SECONDARY Parents' Perception of the Change in Child's Health Compared to One Month Ago - NuBest Group Only (Within-Group Analysis) |
3.17; 3.58; 3.63; 3.71; 3.75; 3.54 | 0.4598 |
| SECONDARY Change in Child's Energy Levels as Reported by Parents - NuBest Group Only (Within-Group Analysis) |
3.88; 4.21; 4.04; 4.29; 4.46; 4.33 | 0.0384 sig |
| SECONDARY Changes in Limitations When Completing High-Intensity Activity - NuBest Group Only (Within-Group Analysis) |
1.13; 1.17; 1.21; 1.17; 1.08; 1.13 | >0.9999 |
| SECONDARY Changes in Limitations When Completing Moderate-Intensity Activity - NuBest Group Only (Within-Group Analysis) |
1.21; 1.13; 1.13; 1.08; 1.00; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations When Moving Around - NuBest Group Only (Within-Group Analysis) |
1.00; 1.08; 1.08; 1.04; 1.00; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations When Walking 100 Meters or Climbing a Flight of Stairs - NuBest Group Only (Within-Group Analysis) |
1.21; 1.08; 1.13; 1.04; 1.04; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations When Bending, Lifting, or Stooping - NuBest Group Only (Within-Group Analysis) |
1.04; 1.08; 1.08; 1.00; 1.00; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations in the Kind of Schoolwork or Activities Undertaken - NuBest Group Only (Within-Group Analysis) |
1.08; 1.13; 1.13; 1.08; 1.00; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations in the Amount of Time Spent Completing Schoolwork or Activities - NuBest Group Only (Within-Group Analysis) |
1.13; 1.25; 1.08; 1.17; 1.00; 1.08 | >0.9999 |
| SECONDARY Changes in Limitations During the Completion of Schoolwork or Activities - NuBest Group Only (Within-Group Analysis) |
1.13; 1.17; 1.21; 1.13; 1.00; 1.08 | >0.9999 |
| SECONDARY Change in Parents' Perception of Child's Health Compared to Other Children - NuBest Group Only (Within-Group Analysis) |
1.71; 1.46; 1.54; 1.29; 1.33; 1.46 | >0.9999 |
| SECONDARY Change in Parents' Perception of Child's Immunity - NuBest Group Only (Within-Group Analysis) |
2.38; 2.21; 2.00; 2.13; 2.13; 2.04 | >0.9999 |
| SECONDARY Change in Parents' Worry About Child's Health - NuBest Group Only (Within-Group Analysis) |
2.38; 2.17; 2.38; 2.13; 2.08; 2.33 | 0.819 |
| SECONDARY Change in Parent-reported Frequency of Child's Stomach Aches - NuBest Group Only (Within-Group Analysis) |
2.42; 2.17; 2.13; 2.08; 2.13; 1.92 | >0.9999 |
| SECONDARY Change in Parent-reported Frequency of Child's Difficulty Going to the Toilet - NuBest Group Only (Within-Group Analysis) |
2.33; 2.13; 1.96; 1.79; 1.71; 1.71 | >0.9999 |
| SECONDARY Changes in Overall Health as Reported by Parents - Placebo Group Only (Within-Group Analysis) |
4.05; 4.19; 4.14; 4.43; 4.19; 4.38 | >0.9999 |
| SECONDARY Change in Parents' Perception of the Child's Health in the Future - Placebo Group Only (Within-Group Analysis) |
3.48; 3.43; 3.48; 3.62; 3.62; 3.62 | >0.9999 |
| SECONDARY Parents' Perception of the Change in Child's Health Compared to One Month Ago - Placebo Group Only (Within-Group Analysis) |
3.29; 3.52; 3.57; 3.90; 3.71; 4.05 | >0.9999 |
| SECONDARY Change in Child's Energy Levels as Reported by Parents - Placebo Group Only (Within-Group Analysis) |
3.86; 3.95; 4.29; 4.33; 4.10; 4.29 | 0.9821 |
| SECONDARY Changes in Limitations When Completing High-Intensity Activity - Placebo Group Only (Within-Group Analysis) |
1.38; 1.24; 1.24; 1.14; 1.14; 1.10 | >0.9999 |
| SECONDARY Changes in Limitations When Completing Moderate-Intensity Activity - Placebo Group Only (Within-Group Analysis) |
1.29; 1.24; 1.19; 1.10; 1.05; 1.10 | >0.9999 |
| SECONDARY Changes in Limitations When Moving Around - Placebo Group Only (Within-Group Analysis) |
1.10; 1.14; 1.10; 1.10; 1.14; 1.10 | >0.9999 |
| SECONDARY Changes in Limitations When Walking 100 Meters or Climbing a Flight of Stairs - Placebo Group Only (Within-Group Analysis) |
1.14; 1.14; 1.05; 1.05; 1.10; 1.05 | >0.9999 |
| SECONDARY Changes in Limitations When Bending, Lifting, or Stooping - Placebo Group Only (Within-Group Analysis) |
1.24; 1.14; 1.10; 1.10; 1.19; 1.05 | >0.9999 |
| SECONDARY Changes in Limitations in the Kind of Schoolwork or Activities Undertaken - Placebo Group Only (Within-Group Analysis) |
1.43; 1.19; 1.19; 1.14; 1.10; 1.10 | >0.9999 |
| SECONDARY Changes in Limitations in the Amount of Time Spent Completing Schoolwork or Activities - Placebo Group Only (Within-Group Analysis) |
1.43; 1.10; 1.19; 1.14; 1.14; 1.10 | >0.9999 |
| SECONDARY Changes in Limitations During the Completion of Schoolwork or Activities - Placebo Group Only (Within-Group Analysis) |
1.48; 1.24; 1.29; 1.10; 1.10; 1.05 | >0.9999 |
| SECONDARY Change in Parents' Perception of Child's Health Compared to Other Children - Placebo Group Only (Within-Group Analysis) |
1.48; 1.57; 1.38; 1.43; 1.48; 1.52 | >0.9999 |
| SECONDARY Change in Parents' Perception of Child's Immunity - Placebo Group Only (Within-Group Analysis) |
2.24; 2.24; 2.19; 2.19; 2.14; 2.00 | >0.9999 |
| SECONDARY Change in Parents' Worry About Child's Health - Placebo Group Only (Within-Group Analysis) |
2.24; 2.19; 2.10; 2.19; 2.14; 2.05 | 0.998 |
| SECONDARY Change in Parent-reported Frequency of Child's Stomach Aches - Placebo Group Only (Within-Group Analysis) |
2.24; 2.05; 1.90; 1.81; 1.90; 1.86 | >0.9999 |
| SECONDARY Change in Parent-reported Frequency of Child's Difficulty Going to the Toilet - Placebo Group Only (Within-Group Analysis) |
1.90; 1.81; 1.71; 1.52; 1.57; 1.48 | >0.9999 |
Summary
A 6-month virtual two-armed randomized double-blind placebo-controlled clinical trial. Participants will take NuBest Tall Growth Protein Powder or a placebo daily. Parents will complete questionnaires at baseline and monthly, and children will undergo cognitive assessments and height/weight measurements at specified intervals.
Eligibility Criteria
Inclusion Criteria
- Interested in their child trialing a dietary supplement designed to improve overall health outcomes in children including height, maintenance of a healthy weight, cognitive function, immune function, and energy levels.
- Willing to refrain from giving their child any vitamins, minerals, or herbal supplements of any kind for the duration of the study.
- Parents willing to weigh and measure the height of their child throughout the study.
- Generally healthy - do not have any uncontrolled chronic disease.
Exclusion Criteria
- Any child with a history of endocrine disorder, heart disease, lung disease, kidney disease, digestive disease, or skeletal dysplasia.
- Any pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.
- Is undergoing or planning to undergo significant medical procedures in the next six months.
- A history of severe allergic reactions, including but not limited to any of the product's ingredients.
- Any child with a dairy allergy or lactose intolerance.
- Has undergone any surgeries or invasive treatments in the last six months.
- Has had any major illness in the last three months.
- Having any planned invasive medical procedures during the study period.
- Currently participating in any other clinical study.
- Unwilling to follow the study protocol.
- Any child diagnosed with attention-deficit disorder (ADD) or attention-deficit hyperactivity disorder (ADHD).
- Any child currently taking or have taken in the last 3 months any prescription medication targeting ADD or ADHD (such as Adderall, Concerta, Focalin, Evekeo, or Ritalin).
- Any child that is a 'fussy' eater or who the parent suspects may not tolerate consuming the test product daily for six months.
Data sourced from ClinicalTrials.gov (NCT06704178). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.