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N/A N=208 Randomized Triple-blind Supportive Care

Digital Dyadic Empowerment Program on Lifestyle Modification for Chronic Kidney Disease Management

Chronic Kidney Diseases

Enrolled (actual)
208
Serious AEs
0.0%
Results posted
Feb 2026
Primary outcome: Primary: Change From Baseline in eGFR at 6 Months (Patient-specific) — -2.35; -4.24 mL/min/1.73m^2

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Digital Dyadic Empowerment (Behavioral); Usual Care (Behavioral)
Age
Adult, Older Adult · 20+ yrs
Sex
All
Sponsor
National Cheng Kung University
Primary completion
Oct 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Change From Baseline in eGFR at 6 Months (Patient-specific)
-2.35; -4.24
SECONDARY
Change From Baseline in CKD Stage at 6 Months (Patient-specific)
6; 1; 37; 31; 7; 11
SECONDARY
Change From Baseline in TTM Stage at 6 Months (Patient-specific)
8; 5; 33; 33; 10; 6
SECONDARY
Change From Baseline in Health Promoting Lifestyle at 6 Months (Patient-specific)
-1.59; 1.87
SECONDARY
Change From Baseline in Dyadic Adjustment at 6 Months
-0.43; -1.22

Summary

The goal of this clinical trial is to find out if the Digital Dyadic Empowerment Program (DDEP) can help people with chronic kidney disease (CKD) and their care partners make healthy lifestyle changes. The main questions this study will answer are: * Does DDEP help protect kidney function? * Does DDEP support healthier daily habits? Researchers will compare two groups: * One group will receive the DDEP and get usual medical care. * The other group will get usual medical care only. Participants will: * Receive usual care with or without DDEP for six months. * Visit the clinic at the start and end of the study for health checks and tests. * Practice healthy habits at home with or without help from DDEP. This study aims to show if adding DDEP to regular care can make it easier for people with CKD and their care partners to live healthier lives.

Eligibility Criteria

Inclusion Criteria

  • The patient has a diagnosis of Chronic Kidney Disease for at least six months;
  • The patient can identify a helpful significant other, and both parties are willing to participate;
  • The patient can communicate in Mandarin or Taiwanese.

Exclusion Criteria

  • The significant other is a healthcare provider;
  • The patient or the significant other has a mental illness diagnosis;
  • The patient is currently receiving renal replacement therapies;
  • Neither the patient nor the significant other uses a smartphone or the LINE messaging app.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06756113). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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