N/A Completed N=60 Randomized Double-blind Treatment

Evaluation of the Efficacy of Laser Acupuncture on Uremic Pruritus

Uremia

Source: ClinicalTrials.gov NCT06875115 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2025

Primary outcomePrimary: Title: Evaluation of the Efficacy of Laser Acupuncture on Ureimc Pruritus — 18.13; 17.47; 10.20; 17.10 points — p=<0.05

Summary

Sixty patients were randomly assigned to either the experimental group (n=30) receiving laser acupuncture or the control group (n=30) receiving sham laser acupuncture. Treatment sessions were conducted during dialysis sessions. The experimental group received laser acupuncture at Xuehai, Quchi, and Bai Chongwo acupoints three times per week for four weeks. The control group received sham laser acupuncture at the same acupoints. The 5-D Pruritus Scale and DLQI were used to assess pruritus severity before and after the intervention.

Outcome Measures

Outcome	Result	p-value
PRIMARY Title: Evaluation of the Efficacy of Laser Acupuncture on Ureimc Pruritus	18.13; 17.47; 10.20; 17.10	<0.05 sig

Eligibility Criteria

Inclusion Criteria

Age ≥ 20 years.
Intact parathyroid hormone (iPTH) levels < 68 pg/mL (patients with -thyroidectomy excluded).
Urea nitrogen (BUN) clearance rate (Kt/V) ≥ 1.2 at each dialysis session.
Serum phosphate levels < 5.5 mg/dL.
Receiving hemodialysis three times weekly for at least three consecutive months.
No history of acute illnesses like infections or cardiovascular disease.
Avoiding a high-phosphorus diet.
Adjusting dialysate calcium concentration to 8.6-10 mg/dL.
Replacing the artificial kidney or increasing dialysis blood flow

Exclusion Criteria

Pregnant or nursing.
History of photosensitivity.
Recent use of systemic or local medications for pruritus (e.g., immunosuppressants, opioid agonists/antagonists, glucocorticoids, antihistamines, ultraviolet B therapy).
Hepatobiliary dysfunction based on medical history and liver function tests.
Malignancies.
Other itchy skin conditions diagnosed by a dermatologist.
Wounds near acupuncture points, contraindicating laser acupuncture

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06875115). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.