N/A
N=60
Evaluation of the Efficacy of Laser Acupuncture on Uremic Pruritus
Uremia
Bottom Line
View on ClinicalTrials.gov: NCT06875115 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcome: Primary: Title: Evaluation of the Efficacy of Laser Acupuncture on Ureimc Pruritus — 18.13; 17.47; 10.20; 17.10 points — p=<0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- laser acupuncture (Device)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Dalin Tzu Chi General Hospital
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Title: Evaluation of the Efficacy of Laser Acupuncture on Ureimc Pruritus |
18.13; 17.47; 10.20; 17.10 | <0.05 sig |
Summary
Sixty patients were randomly assigned to either the experimental group (n=30) receiving laser acupuncture or the control group (n=30) receiving sham laser acupuncture. Treatment sessions were conducted during dialysis sessions. The experimental group received laser acupuncture at Xuehai, Quchi, and Bai Chongwo acupoints three times per week for four weeks. The control group received sham laser acupuncture at the same acupoints. The 5-D Pruritus Scale and DLQI were used to assess pruritus severity before and after the intervention.
Eligibility Criteria
Inclusion Criteria
- Age ≥ 20 years.
- Intact parathyroid hormone (iPTH) levels < 68 pg/mL (patients with -thyroidectomy excluded).
- Urea nitrogen (BUN) clearance rate (Kt/V) ≥ 1.2 at each dialysis session.
- Serum phosphate levels < 5.5 mg/dL.
- Receiving hemodialysis three times weekly for at least three consecutive months.
- No history of acute illnesses like infections or cardiovascular disease.
- Avoiding a high-phosphorus diet.
- Adjusting dialysate calcium concentration to 8.6-10 mg/dL.
- Replacing the artificial kidney or increasing dialysis blood flow
Exclusion Criteria
- Pregnant or nursing.
- History of photosensitivity.
- Recent use of systemic or local medications for pruritus (e.g., immunosuppressants, opioid agonists/antagonists, glucocorticoids, antihistamines, ultraviolet B therapy).
- Hepatobiliary dysfunction based on medical history and liver function tests.
- Malignancies.
- Other itchy skin conditions diagnosed by a dermatologist.
- Wounds near acupuncture points, contraindicating laser acupuncture
Data sourced from ClinicalTrials.gov (NCT06875115). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.