N/A
N=84
Immersive Virtual Reality Exposure for Reducing Preoperative Anxiety in Children
Anxiety State · Satisfaction · Compliance
Bottom Line
View on ClinicalTrials.gov: NCT07018999 ↗Enrolled (actual)
84
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Modified Yale Preoperative Anxiety Scale (mYPAS) (T1) — 31.4; 37.3 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Immersive virtual reality operating theatre tour (Device)
- Age
- Pediatric · 5+ yrs
- Sex
- All
- Sponsor
- Hong Kong Children's Hospital
- Primary completion
- Sep 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Modified Yale Preoperative Anxiety Scale (mYPAS) (T1) |
31.4; 37.3 | — |
| SECONDARY Baseline Preoperative Anxiety Score Using mYPAS on Admission (T0) |
34.8; 36.3 | — |
| SECONDARY Induction Compliance Checklist |
0.824; 1.13 | — |
| SECONDARY Procedure Behaviour Rating Scale PBRS |
1.56; 1.92 | — |
| SECONDARY Parental Anxiety by State-trait Anxiety Inventory (STAI)-T |
39; 41.8 | — |
| SECONDARY Parental Anxiety by State-trait Anxiety Inventory (STAI-S) |
39.6; 43.3 | — |
| SECONDARY Parental Satisfactory Score |
14.5; 14.0 | — |
Summary
Perioperative anxiety management for children undergoing surgery poses a major challenge to anaesthesiologists as high anxiety, reported in numerous studies, leads to detrimental effects physiologically, mentally and on pain scores. Traditional methods, including administration of anxiolytics pre-op has its own limitations e.g. side effects of drugs. Non-pharmacological approaches e.g. OT orientation or information have a heavy reliance on manpower. A sustainable and reliable non-pharmacological method that requires minimal manpower support is needed for the effective management of paediatric perioperative anxiety.
Virtual reality utilises a head-mounted display with visual, auditory and tactile stimuli to simulate a fully immersive 3-dimensional environment. Its application in the paediatric perioperative setting can be either as a distraction during painful procedures or during induction of anaesthesia or as an exposure tool in preoperative education and has demonstrated success in literature.
In a joint project involving the Department of Computing of Hong Kong Polytechnic University, the Department of Computer Science Center for Innovative Applications of Internet and Multimedia Technologies of the City University of Hong Kong and the Hong Kong Children's Hospital (HKCH), an immersive VR operating theatre tour will be designed as part of preoperative education for children. A simulation of the perioperative journey in HKCH operating theatre will be created to help children form realistic expectations of their perioperative journey to cope with their worries about the anticipated procedures.
Eligibility Criteria
Inclusion Criteria
- American Society of Anaesthesiologist (ASA) physical status I or II
- Undergo elective surgical procedures which requires general anaesthesia
- No previous experience of anaesthesia or surgery
Exclusion Criteria
- Patients who are undergoing ultra-major surgery requiring postoperative intensive care unit care.
- Patients who are blind, or with hearing impairment
- Patients with significant developmental or cognitive delays, ADHD or autism
- Patients with history or current symptoms of vertigo
- Patients with history of epilepsy or seizures
- Patients who require anxiolytic premedication
- Patients who have physical conditions that prohibit use of headsets e.g. head / facial injuries, open skin or infectious condition on head/face, head/ facial malformation that precludes proper fitting of the VR headset
- Non-Cantonese speaking patients (due to limited resources of having Cantonese speaking VR design)
- Patients and/or parents/legal guardians who refuse to participate in study
Data sourced from ClinicalTrials.gov (NCT07018999). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.