N/A
N=210
Effect of Bed Bathing Methods on VRE Colonization in ICU Patients
Vancomycin-Resistant Enterococcus
Bottom Line
View on ClinicalTrials.gov: NCT07364435 ↗Enrolled (actual)
210
Serious AEs
0.0%
Results posted
May 2026
Primary outcome: Primary: Vancomycin-Resistant Enterococcus (VRE) Colonization — 0; 0; 30; 33 participants with VRE colonization — p=0.671
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Bed Bath (Procedure); Disposable antibacterial bed bath wipes (Device); Chlorhexidine gluconate 4% (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Özkan Kasap
- Primary completion
- Jan 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Vancomycin-Resistant Enterococcus (VRE) Colonization |
0; 0; 30; 33; 17; 25 | 0.671 |
Summary
This randomized controlled trial aims to compare the effects of two different bed bathing methods on vancomycin-resistant Enterococcus (VRE) colonization in adult intensive care unit patients. A total of 210 patients were randomly assigned to receive either daily whole-body bathing with 4% chlorhexidine gluconate solution or daily bed bathing using disposable antibacterial body wipes. VRE colonization was monitored using skin swab cultures collected on days 7, 14, and 21. The results of this study may contribute to infection prevention strategies in intensive care units by identifying effective hygiene practices for reducing VRE colonization.
Eligibility Criteria
Inclusion Criteria
- Adult patients aged 18 years and older
- Patients admitted to the intensive care unit
- Expected ICU stay of at least 48 hours
- Patients requiring daily bed bathing
Exclusion Criteria
- Known hypersensitivity to chlorhexidine
- Extensive skin lesions or burns
- Patients colonized or infected with VRE at ICU admission
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT07364435). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.