N/A Completed N=78

Evaluation of the Effects of Intraoperative Ventilation Modes on Perioperative Atelectasis

Atelectasis, Postoperative Pulmonary

Source: ClinicalTrials.gov NCT07413575 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2026

Primary outcomePrimary: Change in Lung Ultrasound Score (ΔLUS) From Preoperative Baseline to 24 Hours Postoperatively — 4.92; 3.88; 5.20 scores on a scale — p=0.131

Summary

In hysterectomy surgeries, due to factors such as the abdominal nature of the procedure, prolonged operative duration, and the use of the head-down (Trendelenburg) position during surgery, a lobe or a specific region of the lungs may collapse and fail to fill with air in the postoperative period. This condition is referred to as atelectasis. In this study, the investigators aimed to evaluate the effects of ventilation modes used in the operating room on the development of postoperative atelectasis using lung ultrasonography.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Lung Ultrasound Score (ΔLUS) From Preoperative Baseline to 24 Hours Postoperatively	4.92; 3.88; 5.20	0.131
SECONDARY Mechanical Power During Intraoperative Ventilation	7.05; 6.48; 6.47; 7.00; 6.03; 6.24	—
SECONDARY Arterial Oxygen Partial Pressure (PaO₂)	91.64; 90.96; 90.28; 101.08; 87.88; 85.28	—
SECONDARY PaO₂/FiO₂ Ratio	435.96; 432.76; 429.48; 480.84; 417.88; 405.6	—

Eligibility Criteria

Inclusion Criteria

Patients aged 45 years and older scheduled for hysterectomy surgery with an expected operative duration of more than 2 hours

Patients classified as American Society of Anesthesiologists (ASA) Physical Status Class I, II, or III

Patients for whom planned total intravenous anesthesia was preferred

Exclusion Criteria

Patients younger than 45 years

Patients planned for postoperative intensive care unit monitoring

Patients unable to provide written informed consent

Patients classified as American Society of Anesthesiologists Physical Status Class IV or higher

Patients with a body mass index (BMI) greater than 35

Patients who did not consent to participate in the study

Patients with neuromuscular diseases

Patients with uncontrolled asthma

Patients with chronic obstructive pulmonary disease (COPD), Global Initiative for Chronic Obstructive Lung Disease (GOLD) Class IV

Patients with scoliosis

Patients with a history of pulmonary resection

Patients with chest wall deformities

Patients with a history of spontaneous pneumothorax

Patients for whom inhalational anesthesia was preferred

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT07413575). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.