Clinical Trial Search

Primary: Change From Baseline in the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Total Score — -5.91; -4.91 Scores on a scale — p=0.2202

Primary: Number of Catheter-Related Blood Stream Infections (CRBSI) at 6 Months — 1.98; 2.09; 1.73; 1.02 Infections per 1000 days with catheter

Primary: Percentage of Participants With Treatment Emergent Adverse Events (TEAEs), Serious Adverse Events (SAEs), Grade 3 or Higher TEAEs, and Adverse Event (AE) Leading to…

Primary: Patient Health Questionnaire — 18.04; 16.77; 12.15; 13.09 score on a scale

Primary: Quality of Ultrasound Images — 76.05; 76.14; 75.18; 76.35 score on a scale

Primary: Percent Reduction in the Number of Hand Lentigines as Assessed by Blinded Reviewers.

Primary: 12 Month Retention — 41; 44 Participants — p=0.55

Primary: Feasibility of a Virtual Multicrossover Randomized Control Trial Design as Measured my Completion Rates and Medication Compliance. — 7; 7; 7 Participants

Primary: Endoscopist Evaluation of Colon Cleanliness in the Lubiprostone Group vs the Placebo Group — 1.38; 1.24 score on a scale — p=0.05

Primary: Calculated Blood Loss — 842; 860; 799; 878 CBL (ml)

Primary: Number of Participants With Treatment-related Adverse Events (AEs) Assessed by Physical Examinations — 0; 0 Participants

Primary: Local Injection Site Reactogenicity — 22; 21 participants

Primary: Change From Baseline Typical Weekly Drinking at 1 Month — 1.67; 1.82 typical alcohol drinks consumed per week — p=.985

Primary: Number of Participants Who Survived to Hospital Discharge — 296; 275 Participants

Primary: Change in Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Fatigue Subscale Score — 4.00; 7.00; 8.50; 5.00 score on a scale — p=0.16