Phase 1 N=16 The Interaction of Flavor With Nicotine Form in Adult Smokers
Nicotine Dependence
Primary: Changes in Liking of E-cigarette Overall — 14.2; 5.3; 11.9; 2.2 score on a scale — p=0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=102 A Study of Bendamustine in the Treatment of Chinese Participants With Indolent Non-Hodgkin Lymphoma Refractory to Rituximab Treatment
Non-Hodgkin Lymphoma
Primary: Overall Response Rate (ORR) (Assessed by Independent Review Committee [IRC]) — 73 percentage of participants
N/A N=69 Aligning Medications With What Matters Most
Polypharmacy · Alzheimer Disease and Related Dementias
Primary: Feasibility as Assessed by Proportion of Dyads That Opt Out of the Intervention — 101; 122; 132; 69 Participants
N/A N=32 CoMBAT Opioid Use Disorder: A Combined Medication and Behavioral Activation Treatment for People Living With Opioid Use Disorder
Opioid-use Disorder · Medication Adherence · Health Care Utilization
Primary: Number of Missed Medication Doses - Past 30 Days — 3.13; 2.81; 3.71; 2.25 Number of missed doses — p=0.17
N/A N=107 Evaluation of a Crowd-Powered Web Platform for Depression and Anxiety
Depression, Anxiety
Primary: Depression Scores at Week 16 — 15.7; 15.7 score on a scale — p=0.79
N/A N=30 ANNE Diagnostic Agreement With Home Sleep Testing
Obstructive Sleep Apnea of Adult
Primary: Percent Agreement of ANNE Sleep System to Home Sleep Test (WatchPAT) for Diagnostic Performance to Detect Moderate to Severe Obstructive Sleep Apnea. — 58; 75 percent…
N/A N=122 Study of the AERin Medical Vivaer® ARC Stylus for Nasal AirWAY Obstruction
Nasal Obstruction
Primary: Change in Nasal Obstructive Symptom Evaluation (NOSE) Scores From Baseline to 3 Months — -47.6 score on a scale
Phase 2 N=194 Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma
Ocular Hypertension · Primary Open Angle Glaucoma
Primary: Change From Baseline in Intraocular Pressure at Day 28 (Study Eye) — -6.95; -7.95; -7.04 mmHg — p=0.8070
Phase 2 N=199 Supplements, Placebo, or Rosuvastatin Study
Hypercholesterolemia
Primary: Percent Change in LDL-C From Baseline for Rosuvastatin 5mg Daily Compared With Placebo and Each Dietary Supplement. — -37.86; -2.63; -3.43; 0.42 percent change LDL-C…
N/A N=255 Cranial Electrotherapy Stimulation for the Treatment of Major Depressive Disorder in Adults
Major Depressive Disorder
Primary: Change in the Beck Depression Inventory Second Edition (BDI-II) at Week Two Compared to Baseline. — 16.65; 14.36 units on a scale — p=0.056
Phase 2 N=154 Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Type1 Diabetes Mellitus
Primary: Change in Average Daily Total Insulin Use — -6.72; -5.25; -1.37; -7.59 Units/day
Phase 3 N=90 A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA
Warm Antibody Autoimmune Hemolytic Anemia
Primary: Durable Hemoglobin Response — 16; 12 Participants
Phase 2 N=10 Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome
Sturge-Weber Syndrome
Primary: List Sorting Working Memory Test — 37.14; 39.14 T-score
N/A N=96 Preliminary Effectiveness of Remotely Monitored Blood Alcohol Concentration Device as Treatment Modality
Alcohol Use Disorder
Primary: Alcohol Time Line Follow Back (TLFB) — 27.1; 21 drinks per month
Phase 2 N=45 Evaluation of DEX-IN During Outpatient Procedures
Pain
Primary: Evaluation of Pain Intensity - Mean Pain Score During Procedure — 3.03; 3.10; 4.25 units on a scale