65,437 trials
Intracranial Aneurysm
Primary: Stroke or Death — 8; 5 Participants
Atherosclerotic Cardiovascular Disease · Symptomatic Atherosclerosis · Type2 Diabetes
Primary: Percentage Change in LDL-C From Baseline of the ORION-1 Study to Day 210 in ORION-3 (Inclisiran Arm) — -47.48 Percentage Change
Spider Angioma
Primary: Physician's Global Assessment Scale for Improvement of Spider Angioma — 4.5 score on a scale
Healthy
Primary: Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve of Tirzepatide From Time Zero to Infinity (AUC[0-∞]) — 112000; 111000; 106000 Hour * nanogram per…
Renal Colic
Primary: Pain Score Change — -3.4; -3.6 Units on a Scale — p=0.771
Metastatic Pancreas Cancer · Locally Advanced Pancreatic Cancer · Pancreatic Adenocarcinoma
Primary: Overall Survival — 226; 209 days — p=0.6647
Covid19
Primary: Dose 1 Completion — 14; 243; 253 Participants
Hematologic Neoplasms
Primary: Number of Participants With Adverse Events (AEs), Serious Adverse Events (SAEs), and AEs Leading to Discontinuation — 3; 9; 5; 19 Participants
Suicide · Psychiatric Hospitalization
Primary: Client Satisfaction Questionnaire (CSQ) — 25.00 score on a scale
Healthy
Primary: Urinary Excretion of Tirzepatide Radioactivity Over Time Expressed As A Percentage of the Total Radioactive Dose Administered — 49.56 Percentage of the total radioactive…
Hepatic Insufficiency
Primary: Pharmacokinetics (PK): Area Under The Drug Concentration-Time Curve From Zero To Infinity (AUC[0-∞]) of Tirzepatide — 84300; 102000; 82000; 77000 nanogram*hour per…
Glaucoma, Primary Open Angle · Ocular Hypertension
Primary: Part 2: Mean Change From Baseline in Intraocular Pressure (IOP) at Day 14 - Study Eye — 26.3; 26.1; 27.1; 24.8 millimeters of mercury (mm Hg) — p=<0.001
Postoperative Pain
Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale
Postoperative Pain
Primary: Duration of Analgesia — 541; 634 minutes
Lung Neoplasms · Lung Cancer
Primary: Sensitivity or True Positive Rate (TPR) — 0.854 proportion of lesions