65,437 trials
Diabetes Mellitus
Primary: Emergency Department (ED) Visits Within 30 Days Post Discharge — 0 emergency department visits
Healthy
Primary: Maximum Safinamide Plasma Concentration (Cmax) — 411.5; 792.1; 465.0; 825.3 nanogram/milliliter (ng/mL)
Ovarian Cancer · Fallopian Tube Cancer · Primary Peritoneal Cancer
Primary: Progression-Free Survival (PFS) — 12.32; 22.57 months — p=<.0001
Pseudophakia
Primary: Effect of Angle Kappa in Visual Disturbances — 4; 4; 5; 1 Participants
Grover's Disease · Psoriasis Vulgaris
Primary: Efficacy of Blue Light Therapy for Patients With Grover's Disease — 27; 6 lesion count
HR+/HER2- Locally Advanced, Metastatic Breast Cancer
Primary: Percentage of Participants According to Treatment Lines — 72; 16; 10; 2 Percentage of participants
Healthy Volunteers
Primary: Area Under the Plasma Concentration Versus Time Curve From Time 0 to the Last Quantifiable Concentration (AUC0-t) of Midazolam — 24.2; 50.7 Nanogram Hours per Milliliter…
Migraine
Primary: Percentage of Participants With Freedom From Pain at 2 Hours Post-dose — 23.6; 14.9 Percentage of participants — p=<0.0001
Post ICU Syndrome
Primary: Acceptance With COVID-19 Virtual Post Intensive Care Syndrome (CoV-PICS) Visits - AIM — 4.8 score on a scale
Locally Advanced or Metastatic Urothelial Bladder Cancer
Primary: Objective Response Rate (ORR) as Assessed by Independent Review Committee (IRC) — 24.0 Percentage of participants — p=< 0.0001
Paroxysmal Atrial Fibrillation
Primary: Percentage of Participants With Early Onset Primary Adverse Events (PAEs): Atrio-esophageal Fistula and Pulmonary Vein (PV) Stenosis — 0; 0 Percentage of Participants
Asthma
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) — 54.5 percentage of participants
Solid Tumor · Advanced Solid Tumor
Primary: Part A: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 2; 1; 2; 1 Participants
Refractive Errors
Primary: Least Squares Mean Distance Visual Acuity With Study Lenses at Day 30 — -0.07; -0.07 logMAR
Multiple Myeloma · Non-Hodgkin's Lymphoma
Primary: Number of Participants With Grade 3 or Higher Diarrhea GI Toxicity — 18; 21 Participants