Phase 2 N=169 Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee
Osteoarthritis of the Knee
Primary: Time-to-Exit From Current Study Treatment — 31; 20; NA; NA Days — p=0.1006
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=191 A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)
Dyslipidemia
Primary: Percent Change From Baseline in Low-Density Lipoprotein Cholesterol (LDL-C) (mg/dL) — -0.3; -1.5 Percent Change — p=0.926
Phase 2 N=40 Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers
Smoking · Nicotine Dependence
Primary: Weight Gain in Treatment Completers — 3.35; 4.14 Pounds
Phase 2 N=32 Chemotherapy for Patients With Osteosarcoma
Osteosarcoma
Primary: Percentage of Participants With Tumor Response — 3.1; 0; 3.1; 15.6 percentage of participants
Phase 2 N=150 The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation
Congestive Heart Failure
Primary: The Number of Subjects With Left Ventricular Failure During Left Ventricular Assistance Device (LVAD) Placement After Cardio Pulmonary Bypass, as Determined by Failure…
Phase 2 N=10 Phase II Study of Alendronate Sodium in Children With High-Turnover Idiopathic Juvenile Osteoporosis
Osteoporosis
Primary: Number of Participants With Increased Bone Mineral Density — 10 participants
Phase 2 N=55 Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme
Glioblastoma Multiforme
Primary: Maximal Tolerating Dose (MTD for Phase I) — 3; 3; 6; 3 participants
Phase 2 N=56 The Effect on Blood Cells, Known as Platelets, Using Prasugrel vs Clopidogrel in Patients With the Heart Problem Acute Coronary Syndrome (ACS)
Acute Coronary Syndrome
Primary: Maximum Platelet Aggregation (MPA) to 20 Micromolar (μM) Adenosine Diphosphate (ADP) — 27.1; 40.3 Percentage aggregation — p=<0.001
Phase 2 N=23 GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic Aorta
Aortic Aneurysm, Thoracic
Primary: Freedom From Major Adverse Events and Major Device Events Through 1 Year Post-treatment — 11 Participants
Phase 2 N=420 A Dose-Finding Study of MK0974 in Acute Migraine (MK0974-004)
Migraine
Primary: Pain Relief at 2 Hours — 52; 5; 9; 8 Participants — p=0.015
Phase 2 N=281 The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors
Diabetic Nephropathy · Chronic Kidney Disease
Primary: Change From Baseline to the Last On-treatment Measurement in Urine Albumin to Creatinine Ratio (UACR) Levels Determined From the First Morning Void (FMV) Urine…
Phase 2 N=367 A Placebo Controlled Safety and Efficacy Study of INT131 Besylate in Type 2 Diabetes, With an Active Comparator
Type 2 Diabetes Mellitus
Primary: Change From Baseline in Hemoglobin A1c (HBA1c) at Week 24 With Last Observation Carried Forward — -0.3; -0.6; -0.9; -1.0 Percernt
Phase 2 N=39 A Dose and Schedule Finding Trial With AMG 531 for Chemotherapy Induced Thrombocytopenia (CIT) in Adults With Lymphoma
Chemotherapy-Induced Thrombocytopenia · Hodgkin's Lymphoma · Non-Hodgkin's Lymphoma
Primary: Change in Platelet Nadir — 17.1; 11.2; 5.1; -5.2 10^9/L — p=0.9654
Phase 2 N=32 Safety and Efficacy of GTS21 in Adults With Attention-deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder
Primary: To Assess the Safety and Tolerability of GTS21 (25 mg Tid, 75 mg Tid, 150 mg Tid). — 67; 72; 100 % of subjects
Phase 2 N=175 Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients
Pneumonia
Primary: Colonization of the Oral Cavity by Respiratory Pathogens (on Teeth/Denture/Buccal Mucosa) as Determined by Quantitative Cultures Expressed as Colony Forming Units (Cfu)…