Phase 4 N=83 Effect of Antidepressants on Sex Hormone Levels and Sexual Functioning
Healthy
Primary: Change in 17-OH Pregnenolone — 120; 158; 171; 170 ng/dl — p=>0.8
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=423 A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Primary: The Percentage of Evaluable Participants With at Least One Confirmed Seizure as Adjudicated by the Independent Adjudication Committee (IAC) — 1.1 percentage of…
Phase 4 N=107 A Study of ELIGARD® in Hormone-dependent Prostate Cancer Patients
Prostate Cancer
Primary: Number of Participants With Eligard Related Adverse Events (AE) — 15; 2 Participants
Phase 4 N=226 A Study of Immediate 9 Months Adjuvant Hormone Therapy With Triptorelin 11.25 mg Versus Active Surveillance After Radical Prostatectomy in High Risk Prostate Cancer Patients.
Prostate Cancer
Primary: Number of Subjects With BR Events — 35; 26 Participants
Phase 4 N=74 Modified Pre-operative Oral Doses Acetaminophen Versus Intravenous Acetaminophen
Tonsillectomy · Adenoidectomy
Primary: Total Dose of Opioid — 147.6; 125.4 mcg/kg — p=0.127
Phase 4 N=26 SUBLOCADE Rapid Initiation Study
Opioid-use Disorder
Primary: Participants Who Experienced Any Precipitated Withdrawal Within One Hour After SUBLOCADE Administration — 1 Participants
Phase 4 N=60 A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery
Cataracts
Primary: Number of Subjects With a Change in Bacterial Colonization of Lid and Conjunctival Cultures After 3 Days — 18; 28 Participants
Phase 4 N=13 Trial of an Intervention to Improve Metformin Persistence and Adherence
Metformin Adverse Reaction · Tolerance
Primary: Treatment Satisfaction as Measured by the Treatment Satisfaction Questionnaire for Medication (TSQM II) — 39.42; 51.92 score on a scale
Phase 4 N=10 Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria
Chronic Urticaria
Primary: Change in the Basophil Proteome — 4; 0; 3 Participants
Phase 4 N=41 Treatment of OSA Associated Hypertension With Alpha 2 Agonist or Diuretic
Obstructive Sleep Apnea
Primary: 24-h, Wake and Sleep Period Systolic and Diastolic Blood Pressure — 143; 133; 136; 87 mmHg
Phase 4 N=100 Study of Nivolumab for Advanced Cancers in India
Non-Small Cell Lung Cancer (NSCLC) · Non-Small-Cell Lung Carcinoma · Nonsmall Cell Lung Cancer
Primary: Number of Participants With Treatment-related Adverse Events — 25; 4; 1 Count of participants
Phase 4 N=80 Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.
Anesthetic Effectiveness
Primary: Number of Participants Achieving Pulpal Anesthesia. — 52; 57 Participants
Phase 4 N=56 Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor · Tremor
Primary: Regions With fMRI Differences Between ET and Controls — 139; 93; 85; 74 Number of Activated Voxels
Phase 4 N=49 Trial of Alvimopan in Major Spine Surgery
Constipation
Primary: Time to First Bowel Movement — 50; 64 hours
Phase 4 N=43 Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis
Osteoporosis, Postmenopausal · Periodontitis
Primary: Sost Values for 6th Month — 1389.177; 1085.405; 1596.585; 2131.87 ng/ml — p=<0.01